SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		3 / 3 ASN A  35
ASN A  36
ARG A 197
 None
 0.96A 2rlcA-2qgsA:
undetectable		 2rlcA-2qgsA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		4 / 8 PHE A 137
SER A 169
PHE A 208
LEU A 205
 None
 0.75A 3i45A-2qgsA:
undetectable		 3i45A-2qgsA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		5 / 10 LYS A   9
MET A  14
SER A  16
LEU A  83
LEU A  58
 None
 1.44A 3iltB-2qgsA:
undetectable
3iltE-2qgsA:
undetectable		 3iltB-2qgsA:
21.51
3iltE-2qgsA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		4 / 6 LEU A 205
PHE A 208
ILE A 171
PHE A 139
 None
 0.88A 3ko0B-2qgsA:
undetectable		 3ko0B-2qgsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		4 / 6 LEU A 205
PHE A 208
ILE A 171
PHE A 139
 None
 1.01A 3ko0S-2qgsA:
0.6		 3ko0S-2qgsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		5 / 12 GLN A  75
ALA A  72
LEU A  71
HIS A  20
ILE A  97
 None
 1.08A 3ozwB-2qgsA:
2.1		 3ozwB-2qgsA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		4 / 6 ILE A   7
VAL A  93
PHE A  79
THR A  61
 None
 1.19A 4xe5A-2qgsA:
2.0		 4xe5A-2qgsA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		4 / 6 ASN A  45
THR A 187
PRO A 188
THR A 189
 None
 1.13A 4yoaA-2qgsA:
undetectable		 4yoaA-2qgsA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		5 / 12 GLY A 132
LEU A 178
ARG A 124
MET A 185
ILE A 118
 None
 1.41A 5fepA-2qgsA:
undetectable		 5fepA-2qgsA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 2qgs PROTEIN SE1688
(Staphylococcus
epidermidis) 		5 / 12 GLY A 132
LEU A 178
ARG A 124
MET A 185
ILE A 118
 None
 1.38A 5fesA-2qgsA:
undetectable		 5fesA-2qgsA:
20.42