SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qgx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		5 / 10 PHE A  72
VAL A 122
VAL A  85
VAL A  87
LEU A 130
 None
 0.96A 1fe2A-2qgxA:
undetectable		 1fe2A-2qgxA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 8 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.53A 1iwiA-2qgxA:
undetectable		 1iwiA-2qgxA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 8 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.58A 1t86A-2qgxA:
undetectable		 1t86A-2qgxA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 8 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.63A 2zujA-2qgxA:
undetectable		 2zujA-2qgxA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		5 / 12 GLY A 101
LEU A  98
ILE A 126
ASN A  71
VAL A  85
 None
 1.12A 4fr0A-2qgxA:
undetectable		 4fr0A-2qgxA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 8 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.58A 4l4bA-2qgxA:
undetectable		 4l4bA-2qgxA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 4 TYR A 146
GLY A  94
SER A  93
LEU A  92
 None
 1.44A 5bphC-2qgxA:
undetectable		 5bphC-2qgxA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 7 TRP A 113
ARG A   8
VAL A 122
SER A 121
 None
 1.27A 5umwA-2qgxA:
undetectable
5umwF-2qgxA:
undetectable		 5umwA-2qgxA:
21.47
5umwF-2qgxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		3 / 3 ILE A 103
VAL A  85
PRO A  83
 None
 0.67A 5uunA-2qgxA:
undetectable		 5uunA-2qgxA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1
(Homo
sapiens) 		4 / 8 PHE A  74
VAL A 122
VAL A  29
VAL A  41
 None
 0.57A 6cp4A-2qgxA:
undetectable		 6cp4A-2qgxA:
16.35