SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 10 ALA A  91
LEU A  53
PHE A  79
LEU A  81
ALA A 229
 None
 1.23A 1g5yC-2qh5A:
undetectable		 1g5yC-2qh5A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 12 PHE A 191
HIS A 112
LEU A   8
ILE A  92
ILE A 244
 None
 0.99A 2bxqA-2qh5A:
undetectable		 2bxqA-2qh5A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		3 / 3 ASN A  90
ILE A   6
MET A  98
 None
 0.84A 2h42C-2qh5A:
undetectable		 2h42C-2qh5A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 12 TYR A 183
ILE A 153
VAL A 161
ASN A 157
THR A 138
 None
 1.27A 3a8iC-2qh5A:
0.0		 3a8iC-2qh5A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 8 PHE A 215
SER A 217
LEU A 231
LEU A  80
 None
 1.02A 3i45A-2qh5A:
2.6		 3i45A-2qh5A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		3 / 3 PHE A  28
SER A  36
GLN A  27
 None
 0.99A 3smtA-2qh5A:
undetectable		 3smtA-2qh5A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 8 ILE A 153
VAL A 190
MET A 249
PHE A 164
 None
 0.99A 4r38B-2qh5A:
undetectable		 4r38B-2qh5A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 8 LEU A 200
ALA A 247
ASN A  90
ALA A  96
 None
 0.78A 4wboB-2qh5A:
undetectable		 4wboB-2qh5A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 6 SER A 243
GLY A 187
ASN A 185
ILE A  92
 None
 1.11A 5j4nA-2qh5A:
undetectable		 5j4nA-2qh5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 5 ILE A 255
LEU A 260
GLY A 140
PHE A 139
 None
 0.92A 5kmdC-2qh5A:
undetectable
5kmdD-2qh5A:
undetectable		 5kmdC-2qh5A:
23.05
5kmdD-2qh5A:
23.05