SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 9 LEU A  67
VAL A  91
ILE A  89
VAL A  53
ILE A  50
 None
 1.42A 1gebA-2qh9A:
undetectable		 1gebA-2qh9A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  72
LEU A 111
MET A 108
 None
 0.81A 2itzA-2qh9A:
undetectable		 2itzA-2qh9A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 11 ILE A  70
ALA A 124
GLY A 125
GLU A 126
GLY A 139
 None
 0.95A 4e47A-2qh9A:
undetectable		 4e47A-2qh9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 11 ILE A  70
ALA A 124
GLY A 125
GLU A 126
GLY A 139
 None
 0.92A 4e47C-2qh9A:
undetectable		 4e47C-2qh9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  80
LEU A  67
LYS A  48
ILE A  50
 None
 0.84A 4hb8A-2qh9A:
undetectable		 4hb8A-2qh9A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 11 ILE A  70
ALA A 124
GLY A 125
GLU A 126
GLY A 139
 None
 0.93A 4jdsC-2qh9A:
undetectable		 4jdsC-2qh9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  70
ALA A 124
GLY A 125
GLU A 126
GLY A 139
 None
 0.92A 4jlgA-2qh9A:
undetectable		 4jlgA-2qh9A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 11 ILE A  70
ALA A 124
GLY A 125
GLU A 126
GLY A 139
 None
 0.93A 5ayfA-2qh9A:
undetectable		 5ayfA-2qh9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		3 / 3 ILE A   9
ILE A  80
MET A  52
 None
 0.68A 5i9yA-2qh9A:
undetectable		 5i9yA-2qh9A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		5 / 10 TYR A 134
ILE A 127
ILE A 135
ILE A  70
ILE A  80
 None
 1.08A 5murE-2qh9A:
undetectable		 5murE-2qh9A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		3 / 3 THR A 137
ALA A 145
LYS A 147
 None
 0.61A 6fgcA-2qh9A:
undetectable		 6fgcA-2qh9A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 2qh9 UPF0215 PROTEIN
AF_1433
(Archaeoglobus
fulgidus) 		3 / 3 THR A 137
ALA A 145
LYS A 147
 None
 0.60A 6fgdA-2qh9A:
undetectable		 6fgdA-2qh9A:
16.67