SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 None
 0.36A 1th6A-2qheA:
22.5		 1th6A-2qheA:
66.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 7 GLY A  31
HIS A  48
TYR A  52
PRO A  68
 None
 0.69A 1th6A-2qheA:
22.5		 1th6A-2qheA:
66.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 None
 0.39A 2armA-2qheA:
22.5		 2armA-2qheA:
66.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 7 GLY A  31
HIS A  48
TYR A  52
PRO A  68
 None
 0.72A 2armA-2qheA:
22.5		 2armA-2qheA:
66.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 6 ARG A  72
ASP A  71
THR A  70
LYS A  92
 None
 1.29A 2j2pE-2qheA:
undetectable
2j2pF-2qheA:
undetectable		 2j2pE-2qheA:
18.60
2j2pF-2qheA:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 9 VAL A   2
VAL A   3
GLY A   6
PRO A  18
THR A  23
GLY A  30
 None
 0.76A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		11 / 11 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
SER A  17
PRO A  18
PRO A  20
SER A  21
THR A  23
LYS A 115
 None
 0.76A 3bjwB-2qheA:
24.1		 3bjwB-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.71A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 7 LYS A   7
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.61A 3bjwB-2qheA:
24.1		 3bjwB-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 7 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.51A 3bjwB-2qheA:
24.1		 3bjwB-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 9 LYS A  16
TYR A 113
LYS A 116
TYR A 117
PRO A 121
 None
 1.45A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 10 VAL A   2
VAL A   3
GLU A   4
GLY A   6
PRO A  18
THR A  23
 None
 0.61A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
GLN A  11
PHE A  19
 None
 0.60A 3bjwH-2qheA:
23.8		 3bjwH-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 7 VAL A   2
VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
 1.39A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 6 VAL A   2
VAL A   3
GLN A  11
PHE A  19
 None
 0.56A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 6 VAL A   2
VAL A   3
PHE A  19
ARG A  72
 None
 1.16A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 11 GLY A   6
ILE A  10
LYS A  16
SER A  17
SER A  21
LYS A 115
 None
 1.00A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		9 / 11 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
SER A  17
PRO A  20
SER A  21
THR A  23
 None
 0.77A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		9 / 11 VAL A   2
LEU A   5
GLY A   6
LYS A  16
SER A  17
PRO A  18
PRO A  20
SER A  21
THR A  23
 None
 0.80A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 9 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 1.28A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 9 LYS A  16
TYR A 113
LYS A 116
TYR A 117
PRO A 121
 None
 1.42A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 6 VAL A   2
GLY A  14
ARG A 107
LEU A 110
 None
 0.97A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 6 VAL A   3
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.45A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
THR A  23
THR A  70
ARG A  72
 None
 1.17A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.79A 3bjwG-2qheA:
22.6		 3bjwG-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 ILE A  10
PRO A  18
PHE A  19
PRO A  20
 None
 0.33A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 12 ILE A   9
LYS A  16
PRO A  18
PHE A  19
PRO A  20
SER A  21
 None
 1.46A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		8 / 12 VAL A   2
ILE A  10
LYS A  16
PRO A  18
PHE A  19
SER A  21
THR A  23
LYS A 115
 None
 0.74A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		10 / 12 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
PRO A  18
PHE A  19
PRO A  20
SER A  21
THR A  23
 None
 0.58A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		9 / 12 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
SER A  17
PRO A  18
PRO A  20
SER A  21
 None
 0.76A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.76A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 8 LYS A  16
TYR A 113
ASN A 114
PRO A 121
 None
 1.29A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 8 LYS A 116
PRO A 121
PHE A 124
TRP A 125
 None
 0.96A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 7 LYS A   7
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.95A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 7 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.49A 3bjwF-2qheA:
23.9		 3bjwF-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 8 VAL A   2
VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
 1.36A 3bjwA-2qheA:
22.8		 3bjwA-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
GLN A  11
PHE A  19
 None
 0.56A 3bjwB-2qheA:
24.1		 3bjwB-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH504_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 4 PRO A 121
ASN A 122
PHE A 124
TRP A 125
 None
 1.11A 3bjwE-2qheA:
23.7		 3bjwE-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		11 / 11 VAL A   2
LEU A   5
GLY A   6
ILE A  10
LYS A  16
SER A  17
PRO A  18
PRO A  20
SER A  21
THR A  23
LYS A 115
 None
 1.00A 3bjwH-2qheA:
23.8		 3bjwH-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 9 LYS A  16
TYR A 113
ASN A 114
TYR A 117
PRO A 121
 None
 1.33A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_1
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		5 / 9 LYS A  16
TYR A 113
LYS A 116
TYR A 117
PRO A 121
 None
 1.45A 3bjwC-2qheA:
22.8		 3bjwC-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
THR A  23
THR A  70
ARG A  72
 None
 1.27A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 VAL A   2
VAL A   3
THR A  23
THR A  70
 None
 0.69A 3bjwD-2qheA:
22.8		 3bjwD-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		6 / 7 VAL A   3
ILE A  10
GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.59A 3bjwH-2qheA:
23.8		 3bjwH-2qheA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 5 HIS A  48
TYR A  52
PRO A  68
LYS A  69
 None
 0.46A 3fo7A-2qheA:
22.6		 3fo7A-2qheA:
66.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 2qhe PHOSPHOLIPASE A2
(Echis
carinatus) 		4 / 6 GLU A  33
PRO A  36
ARG A  34
GLY A  32
 None
 1.42A 3oxvA-2qheA:
undetectable		 3oxvA-2qheA:
20.34