SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LYS A 205
LEU A 202
ALA A 204
LEU A 211
 EDO  A 298 (-2.7A)
EDO  A 298 (-4.9A)
None
None
 1.04A 1etb1-2qhpA:
undetectable		 1etb1-2qhpA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 117
GLY A 243
THR A 249
ALA A 250
VAL A  33
 None
 0.97A 1jg4A-2qhpA:
2.3		 1jg4A-2qhpA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 241
ASP A 240
GLY A 281
ILE A  22
ALA A  11
 None
 1.22A 1oltA-2qhpA:
3.7		 1oltA-2qhpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LYS A 205
LEU A 202
ALA A 204
LEU A 211
 EDO  A 298 (-2.7A)
EDO  A 298 (-4.9A)
None
None
 1.10A 1tt6B-2qhpA:
undetectable		 1tt6B-2qhpA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 0.97A 2eilP-2qhpA:
undetectable
2eilW-2qhpA:
undetectable		 2eilP-2qhpA:
21.57
2eilW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 0.97A 2eimP-2qhpA:
undetectable
2eimW-2qhpA:
undetectable		 2eimP-2qhpA:
21.57
2eimW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  23
GLY A  24
ASN A  28
GLY A 243
ASP A 246
 None
 0.75A 2pkkA-2qhpA:
26.8		 2pkkA-2qhpA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  92
PHE A 168
ALA A 204
LEU A 181
MET A 187
 None
EDO  A 298 ( 4.9A)
None
None
None
 1.08A 2x2nD-2qhpA:
undetectable		 2x2nD-2qhpA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 1.03A 3asnP-2qhpA:
undetectable
3asnW-2qhpA:
undetectable		 3asnP-2qhpA:
21.57
3asnW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 1.05A 3asoP-2qhpA:
undetectable
3asoW-2qhpA:
undetectable		 3asoP-2qhpA:
21.57
3asoW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 VAL A 222
ILE A 256
ILE A 212
LEU A 211
 None
 0.59A 3hegA-2qhpA:
undetectable		 3hegA-2qhpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 154
ILE A 184
PHE A 223
GLU A 180
ASP A 178
 None
 1.39A 3ko0A-2qhpA:
undetectable
3ko0B-2qhpA:
undetectable
3ko0C-2qhpA:
undetectable
3ko0D-2qhpA:
undetectable		 3ko0A-2qhpA:
16.61
3ko0B-2qhpA:
16.61
3ko0C-2qhpA:
16.61
3ko0D-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLU A 180
ASP A 178
LEU A 154
ILE A 184
PHE A 223
 None
 1.44A 3ko0C-2qhpA:
undetectable
3ko0D-2qhpA:
undetectable
3ko0E-2qhpA:
undetectable
3ko0F-2qhpA:
undetectable		 3ko0C-2qhpA:
16.61
3ko0D-2qhpA:
16.61
3ko0E-2qhpA:
16.61
3ko0F-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 154
ILE A 184
PHE A 223
GLU A 180
ASP A 178
 None
 1.41A 3ko0C-2qhpA:
undetectable
3ko0D-2qhpA:
undetectable
3ko0E-2qhpA:
undetectable
3ko0F-2qhpA:
undetectable		 3ko0C-2qhpA:
16.61
3ko0D-2qhpA:
16.61
3ko0E-2qhpA:
16.61
3ko0F-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLU A 180
ASP A 178
LEU A 154
ILE A 184
PHE A 223
 None
 1.48A 3ko0E-2qhpA:
undetectable
3ko0F-2qhpA:
undetectable
3ko0G-2qhpA:
undetectable
3ko0H-2qhpA:
undetectable		 3ko0E-2qhpA:
16.61
3ko0F-2qhpA:
16.61
3ko0G-2qhpA:
16.61
3ko0H-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 180
ASP A 178
LEU A 154
ILE A 184
PHE A 223
 None
 1.38A 3ko0G-2qhpA:
undetectable
3ko0H-2qhpA:
undetectable
3ko0I-2qhpA:
undetectable
3ko0J-2qhpA:
undetectable		 3ko0G-2qhpA:
16.61
3ko0H-2qhpA:
16.61
3ko0I-2qhpA:
16.61
3ko0J-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 154
ILE A 184
PHE A 223
GLU A 180
ASP A 178
 None
 1.49A 3ko0O-2qhpA:
undetectable
3ko0P-2qhpA:
undetectable
3ko0Q-2qhpA:
0.0
3ko0R-2qhpA:
undetectable		 3ko0O-2qhpA:
16.61
3ko0P-2qhpA:
16.61
3ko0Q-2qhpA:
16.61
3ko0R-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 154
ILE A 184
PHE A 223
GLU A 180
ASP A 178
 None
 1.41A 3ko0O-2qhpA:
undetectable
3ko0P-2qhpA:
undetectable
3ko0Q-2qhpA:
0.0
3ko0R-2qhpA:
undetectable		 3ko0O-2qhpA:
16.61
3ko0P-2qhpA:
16.61
3ko0Q-2qhpA:
16.61
3ko0R-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLU A 180
ASP A 178
LEU A 154
ILE A 184
PHE A 223
 None
 1.42A 3ko0Q-2qhpA:
0.0
3ko0R-2qhpA:
undetectable
3ko0S-2qhpA:
undetectable
3ko0T-2qhpA:
undetectable		 3ko0Q-2qhpA:
16.61
3ko0R-2qhpA:
16.61
3ko0S-2qhpA:
16.61
3ko0T-2qhpA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 154
ASP A 151
THR A 214
GLY A 245
ASP A 246
 None
 1.28A 3sfuC-2qhpA:
undetectable		 3sfuC-2qhpA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 164
PHE A 168
ILE A 149
ASN A 153
 None
EDO  A 298 ( 4.9A)
None
None
 1.02A 5n5dA-2qhpA:
3.9		 5n5dA-2qhpA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 1.02A 5x19P-2qhpA:
undetectable		 5x19P-2qhpA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 208
PHE A 223
LEU A 174
PHE A 168
 None
None
None
EDO  A 298 ( 4.9A)
 1.15A 5x1fC-2qhpA:
undetectable
5x1fJ-2qhpA:
undetectable		 5x1fC-2qhpA:
21.57
5x1fJ-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 175
LEU A 174
PHE A 168
LEU A 202
 None
None
EDO  A 298 ( 4.9A)
EDO  A 298 (-4.9A)
 0.98A 5x1fP-2qhpA:
undetectable
5x1fW-2qhpA:
undetectable		 5x1fP-2qhpA:
21.57
5x1fW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 208
PHE A 223
LEU A 174
PHE A 168
 None
None
None
EDO  A 298 ( 4.9A)
 1.14A 5xdxC-2qhpA:
undetectable
5xdxJ-2qhpA:
undetectable		 5xdxC-2qhpA:
21.17
5xdxJ-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 208
PHE A 223
LEU A 174
PHE A 168
 None
None
None
EDO  A 298 ( 4.9A)
 1.18A 5xdxP-2qhpA:
undetectable
5xdxW-2qhpA:
undetectable		 5xdxP-2qhpA:
21.17
5xdxW-2qhpA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 2qhp FRUCTOKINASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 149
ASP A 151
ALA A 116
ALA A 251
LEU A 257
 None
 0.91A 6bq4A-2qhpA:
3.1		 6bq4A-2qhpA:
16.25