SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qie'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 2qie MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Staphylococcus
aureus) 		5 / 11 ILE A  78
ILE A  67
ILE A 115
GLU A 113
VAL A  96
 None
 1.06A 3tmzA-2qieA:
undetectable		 3tmzA-2qieA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 2qie MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Staphylococcus
aureus) 		4 / 5 SER A  77
HIS A  80
TYR A  16
VAL A  92
 None
 1.36A 4eohB-2qieA:
undetectable		 4eohB-2qieA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2qie MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Staphylococcus
aureus) 		3 / 3 LYS A 102
TYR A 105
ARG A 106
 None
 1.22A 4gc9A-2qieA:
undetectable		 4gc9A-2qieA:
18.96