SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		3 / 3 GLN A  81
ILE A  80
TYR A  79
 EDO  A 305 (-4.2A)
EDO  A 301 (-4.0A)
EDO  A 301 ( 4.4A)
 0.63A 1vifA-2qipA:
undetectable		 1vifA-2qipA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		4 / 6 PHE A  63
ILE A  66
VAL A  70
PHE A  72
 None
 0.93A 2cizA-2qipA:
undetectable		 2cizA-2qipA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		4 / 8 ILE A 110
LYS A  43
GLU A   7
ILE A   9
 None
 0.95A 2j9dJ-2qipA:
undetectable
2j9dK-2qipA:
undetectable
2j9dL-2qipA:
undetectable		 2j9dJ-2qipA:
23.03
2j9dK-2qipA:
23.03
2j9dL-2qipA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		4 / 8 PRO A 104
VAL A 109
LEU A  12
ILE A 100
 None
 0.88A 3u5kD-2qipA:
undetectable		 3u5kD-2qipA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		5 / 11 ALA A  10
ILE A 102
ILE A 100
LEU A 121
ILE A 125
 None
 1.05A 4dt8A-2qipA:
undetectable		 4dt8A-2qipA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		5 / 10 ALA A  10
ILE A 102
ILE A 100
LEU A 121
ILE A 125
 None
 1.01A 4dt8B-2qipA:
undetectable		 4dt8B-2qipA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		5 / 10 ALA A  10
ILE A 102
ILE A 100
LEU A 121
ILE A 125
 None
 1.04A 4dtaA-2qipA:
undetectable		 4dtaA-2qipA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		4 / 8 LEU A  12
LEU A 111
VAL A 109
ILE A 125
 None
 0.88A 4oj4A-2qipA:
undetectable		 4oj4A-2qipA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982
(Vibrio
parahaemolyticus) 		5 / 12 ASP A  92
LEU A 111
SER A  47
GLU A 101
GLY A  94
 None
 1.30A 5il1A-2qipA:
undetectable		 5il1A-2qipA:
20.59