SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 VAL A 223
GLY A 222
LEU A 175
GLU A 205
 None
 0.69A 1fduD-2qj8A:
undetectable		 1fduD-2qj8A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ASN A  87
ILE A  86
GLU A 119
GLY A 111
 None
 0.96A 1meiA-2qj8A:
undetectable		 1meiA-2qj8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ALA A  74
GLN A  75
ILE A  80
ILE A  82
 None
 0.92A 1p7lD-2qj8A:
undetectable		 1p7lD-2qj8A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ALA A  74
GLN A  75
ILE A  80
ILE A  82
 None
 0.92A 1p7lC-2qj8A:
undetectable		 1p7lC-2qj8A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ALA A  74
GLN A  75
ILE A  80
ILE A  82
 None
 0.92A 1rg9D-2qj8A:
undetectable		 1rg9D-2qj8A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 LEU A   7
VAL A 132
LEU A  48
VAL A  83
 None
 0.99A 2bdmA-2qj8A:
undetectable		 2bdmA-2qj8A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ASN A  97
ARG A  96
ASP A 138
 None
 0.96A 2qe6A-2qj8A:
undetectable		 2qe6A-2qj8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		3 / 3 ASN A  97
ARG A  96
ASP A 138
 None
 0.97A 2qe6B-2qj8A:
undetectable		 2qe6B-2qj8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		5 / 10 ARG A 300
ILE A 299
ALA A 301
LEU A 325
VAL A 277
 None
 1.23A 3o02A-2qj8A:
undetectable
3o02B-2qj8A:
undetectable		 3o02A-2qj8A:
22.22
3o02B-2qj8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 SER A 118
ILE A 121
PHE A 109
GLU A 119
 None
 1.11A 4cx7A-2qj8A:
undetectable
4cx7B-2qj8A:
undetectable		 4cx7A-2qj8A:
21.95
4cx7B-2qj8A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 SER A 118
ILE A 121
PHE A 109
GLU A 119
 None
 1.19A 4cx7C-2qj8A:
undetectable
4cx7D-2qj8A:
undetectable		 4cx7C-2qj8A:
21.95
4cx7D-2qj8A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 PHE A 206
GLY A  60
LEU A  63
ILE A  49
 None
 0.84A 4em2A-2qj8A:
undetectable		 4em2A-2qj8A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 ALA A  74
GLN A  75
ILE A  80
ILE A  82
 None
 0.87A 4kttB-2qj8A:
undetectable		 4kttB-2qj8A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 8 LEU A  21
LEU A  34
VAL A  83
ILE A  86
 None
 0.92A 4oj4A-2qj8A:
undetectable		 4oj4A-2qj8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		5 / 12 GLY A 222
GLY A 226
ALA A 237
ILE A 218
LEU A 175
 None
 1.12A 5bw4B-2qj8A:
undetectable		 5bw4B-2qj8A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 THR A 145
GLY A 208
GLU A 205
HIS A 140
 None
 1.25A 5c0oH-2qj8A:
undetectable		 5c0oH-2qj8A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		5 / 11 ALA A 124
VAL A  36
LEU A  34
LEU A 105
VAL A  83
 None
 1.30A 5eb5A-2qj8A:
undetectable		 5eb5A-2qj8A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 7 GLY A 115
GLY A 111
PHE A 109
LEU A 105
 None
 0.72A 5izfA-2qj8A:
undetectable		 5izfA-2qj8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		5 / 11 GLN A  75
VAL A 132
ASP A 134
THR A 135
LEU A  11
 None
 1.47A 5jh7B-2qj8A:
4.8		 5jh7B-2qj8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 ILE A 218
ILE A  49
PHE A 206
PHE A  37
 None
 0.93A 5vkqB-2qj8A:
undetectable
5vkqC-2qj8A:
undetectable		 5vkqB-2qj8A:
11.09
5vkqC-2qj8A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 ILE A 218
ILE A  49
PHE A 206
PHE A  37
 None
 0.93A 5vkqC-2qj8A:
undetectable
5vkqD-2qj8A:
undetectable		 5vkqC-2qj8A:
11.09
5vkqD-2qj8A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 ALA A  90
GLY A  51
THR A  50
ILE A 125
 None
 0.89A 6f8cA-2qj8A:
undetectable		 6f8cA-2qj8A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2qj8 MLR6093 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 LEU A 193
THR A 192
THR A 186
GLY A 188
 None
 1.24A 6gtqA-2qj8A:
undetectable		 6gtqA-2qj8A:
19.17