SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		4 / 8 ALA A 150
LEU A 148
LEU A 134
ALA A 138
 None
 0.81A 1e7cA-2qjgA:
undetectable		 1e7cA-2qjgA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.86A 1sdtB-2qjgA:
undetectable		 1sdtB-2qjgA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.85A 2avoB-2qjgA:
undetectable		 2avoB-2qjgA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A 213
ILE A 256
VAL A 257
HIS A 258
VAL A  28
 None
 1.28A 2g72B-2qjgA:
undetectable		 2g72B-2qjgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 MET A 146
LEU A  86
SER A 117
LEU A  63
VAL A  69
 None
 1.11A 2hrcA-2qjgA:
undetectable		 2hrcA-2qjgA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.71A 2o4lB-2qjgA:
undetectable		 2o4lB-2qjgA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.90A 2o4sB-2qjgA:
undetectable		 2o4sB-2qjgA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 MET A 146
LEU A  86
SER A 117
LEU A  63
VAL A  69
 None
 1.17A 2po5A-2qjgA:
undetectable		 2po5A-2qjgA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 11 MET A 146
LEU A  86
SER A 117
LEU A  63
VAL A  69
 None
 1.16A 2po5B-2qjgA:
undetectable		 2po5B-2qjgA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.91A 2q5kB-2qjgA:
undetectable		 2q5kB-2qjgA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.75A 2q63A-2qjgA:
undetectable		 2q63A-2qjgA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.73A 2qakA-2qjgA:
undetectable		 2qakA-2qjgA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.88A 2r5pB-2qjgA:
undetectable		 2r5pB-2qjgA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.88A 2r5pD-2qjgA:
undetectable		 2r5pD-2qjgA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 10 GLY A 248
ASP A  53
GLY A  58
VAL A 236
ILE A 240
 None
None
None
F2P  A 501 (-3.8A)
None
 0.89A 3em3A-2qjgA:
undetectable		 3em3A-2qjgA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.67A 3jw2B-2qjgA:
undetectable		 3jw2B-2qjgA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		3 / 3 ARG A 132
VAL A 105
THR A 140
 None
 0.87A 3k4vA-2qjgA:
undetectable		 3k4vA-2qjgA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 9 GLY A 179
ALA A 180
ASP A 181
ILE A 182
ILE A 137
 None
 0.84A 3ogpA-2qjgA:
undetectable		 3ogpA-2qjgA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 182
 None
 0.53A 3ogqB-2qjgA:
undetectable		 3ogqB-2qjgA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 9 GLY A 248
ASP A  53
GLY A  58
VAL A 236
ILE A 240
 None
None
None
F2P  A 501 (-3.8A)
None
 0.96A 3oxvA-2qjgA:
undetectable		 3oxvA-2qjgA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 10 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 1.01A 3oxwC-2qjgA:
undetectable		 3oxwC-2qjgA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 10 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.77A 3oxwC-2qjgA:
undetectable		 3oxwC-2qjgA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		3 / 3 ARG A 132
VAL A 105
THR A 140
 None
 0.88A 3tl9A-2qjgA:
undetectable		 3tl9A-2qjgA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		4 / 8 GLY A 112
ALA A 113
ASP A 114
THR A 103
 None
 0.86A 4eyrB-2qjgA:
undetectable		 4eyrB-2qjgA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  39
ILE A  47
ARG A 238
HIS A  65
LEU A  64
 None
None
F2P  A 501 (-3.9A)
None
None
 1.04A 4iv0A-2qjgA:
undetectable		 4iv0A-2qjgA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 174
GLY A 179
ALA A 180
ASP A 181
ILE A 149
 None
 0.72A 4jecA-2qjgA:
undetectable		 4jecA-2qjgA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  39
ILE A  47
ARG A 238
HIS A  65
LEU A  64
 None
None
F2P  A 501 (-3.9A)
None
None
 1.03A 4mwzA-2qjgA:
undetectable		 4mwzA-2qjgA:
27.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  39
ILE A  47
ARG A 238
HIS A  65
LEU A  64
 None
None
F2P  A 501 (-3.9A)
None
None
 1.03A 4mwzB-2qjgA:
undetectable		 4mwzB-2qjgA:
27.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A  37
GLY A  35
ILE A  29
ALA A 235
GLY A 237
 F2P  A 501 (-3.2A)
None
None
None
F2P  A 501 (-3.6A)
 1.09A 4r29D-2qjgA:
undetectable		 4r29D-2qjgA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 VAL A  36
THR A 104
VAL A 105
ILE A 118
HIS A  85
 None
 1.39A 4s0vA-2qjgA:
undetectable		 4s0vA-2qjgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 9 HIS A  65
GLY A  89
GLY A  88
ASP A  33
HIS A  85
 None
None
None
F2P  A 501 (-3.5A)
None
 1.20A 5f8yA-2qjgA:
0.0		 5f8yA-2qjgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 8 HIS A  65
GLY A  89
GLY A  88
ASP A  33
HIS A  85
 None
None
None
F2P  A 501 (-3.5A)
None
 1.24A 5f8yA-2qjgA:
undetectable		 5f8yA-2qjgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 9 HIS A  65
GLY A  89
GLY A  88
ASP A  33
HIS A  85
 None
None
None
F2P  A 501 (-3.5A)
None
 1.23A 5f8yA-2qjgA:
undetectable		 5f8yA-2qjgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 9 HIS A  65
GLY A  89
GLY A  88
ASP A  33
HIS A  85
 None
None
None
F2P  A 501 (-3.5A)
None
 1.20A 5f8yB-2qjgA:
undetectable		 5f8yB-2qjgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 11 ILE A  83
THR A  27
VAL A 206
VAL A 183
MET A 151
 None
None
None
None
F2P  A 501 (-3.3A)
 1.43A 5jkwA-2qjgA:
undetectable		 5jkwA-2qjgA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A 179
ASP A 181
ILE A 149
 None
 0.62A 6dgxB-2qjgA:
undetectable		 6dgxB-2qjgA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.90A 6dj1B-2qjgA:
undetectable		 6dj1B-2qjgA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 2qjg PUTATIVE ALDOLASE
MJ0400
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A 179
ALA A 180
ASP A 181
ILE A 149
VAL A 120
 None
 0.91A 6dj2B-2qjgA:
undetectable		 6dj2B-2qjgA:
15.87