SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
5 / 12 LEU A 152
ILE A 120
ARG A 118
TYR A 239
THR A 186
None
1.19A 1ddrB-2qjvA:
undetectable
1ddrB-2qjvA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 5 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.11A 1os2A-2qjvA:
undetectable
1os2A-2qjvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.12A 1os2D-2qjvA:
undetectable
1os2D-2qjvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
1.01A 1p6kA-2qjvA:
undetectable
1p6kA-2qjvA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
1.01A 1p6kB-2qjvA:
undetectable
1p6kB-2qjvA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.95A 1rs6A-2qjvA:
undetectable
1rs6A-2qjvA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.98A 1rs6B-2qjvA:
undetectable
1rs6B-2qjvA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.99A 1rs7B-2qjvA:
undetectable
1rs7B-2qjvA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.13A 1utzA-2qjvA:
undetectable
1utzA-2qjvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.16A 1utzB-2qjvA:
undetectable
1utzB-2qjvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.97A 1zzqA-2qjvA:
undetectable
1zzqA-2qjvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.99A 1zzqB-2qjvA:
undetectable
1zzqB-2qjvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
1.05A 1zzuA-2qjvA:
undetectable
1zzuA-2qjvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
1.04A 1zzuB-2qjvA:
undetectable
1zzuB-2qjvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.13A 2hu6A-2qjvA:
undetectable
2hu6A-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.09A 2ow9B-2qjvA:
undetectable
2ow9B-2qjvA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.09A 2ozrC-2qjvA:
undetectable
2ozrC-2qjvA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.06A 2ozrD-2qjvA:
undetectable
2ozrD-2qjvA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 5 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.14A 3likA-2qjvA:
undetectable
3likA-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.15A 3lilA-2qjvA:
undetectable
3lilA-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 5 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.11A 3lkaA-2qjvA:
undetectable
3lkaA-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.88A 3n62A-2qjvA:
undetectable
3n62A-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.93A 3n62B-2qjvA:
undetectable
3n62B-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.96A 3n66B-2qjvA:
undetectable
3n66B-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
5 / 12 PHE A 191
TYR A 240
ALA A 163
THR A 232
ILE A 233
None
1.27A 3ndiA-2qjvA:
undetectable
3ndiA-2qjvA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
5 / 11 PRO A  77
ARG A  80
SER A  76
HIS A 140
ILE A  81
None
SO4  A 276 (-3.8A)
None
None
None
1.38A 3rf4A-2qjvA:
undetectable
3rf4C-2qjvA:
undetectable
3rf4A-2qjvA:
18.87
3rf4C-2qjvA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
5 / 12 ALA A  94
LEU A  88
TYR A  84
ILE A  81
LEU A  58
MLY  A  95 ( 3.3A)
None
None
None
None
1.23A 5eshA-2qjvA:
undetectable
5eshA-2qjvA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 4 HIS A 228
GLU A 185
HIS A 172
HIS A 170
NI  A 271 (-3.4A)
NI  A 271 (-2.6A)
NI  A 271 (-3.3A)
NI  A 271 (-3.4A)
1.14A 5n5jA-2qjvA:
undetectable
5n5jA-2qjvA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.90A 5vunA-2qjvA:
undetectable
5vunA-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.99A 5vunB-2qjvA:
undetectable
5vunB-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.97A 5vuoB-2qjvA:
undetectable
5vuoB-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 LEU A 104
ILE A  71
ALA A  94
LEU A  88
None
None
MLY  A  95 ( 3.3A)
None
0.81A 5y7pC-2qjvA:
undetectable
5y7pC-2qjvA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 8 ARG A 190
ASN A 217
GLN A 195
PHE A 191
SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
0.95A 6auuB-2qjvA:
undetectable
6auuB-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica)
4 / 7 VAL A 223
ILE A  18
GLY A 111
ALA A 245
MLY  A 222 ( 3.1A)
MLY  A 222 ( 4.9A)
None
None
0.80A 6hd6B-2qjvA:
undetectable
6hd6B-2qjvA:
18.47