SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  13
LEU A  16
ASN A  17
LEU A  20
GLN A  38
 None
 1.40A 1a28B-2qjxA:
undetectable		 1a28B-2qjxA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OAF_A_ASCA1253_0
(ASCORBATE PEROXIDASE)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		4 / 6 CYH A  37
LEU A  47
HIS A  76
ARG A  75
 None
 1.48A 1oafA-2qjxA:
0.0		 1oafA-2qjxA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  13
LEU A  16
ASN A  17
LEU A  20
GLN A  38
 None
 1.41A 1sqnA-2qjxA:
undetectable		 1sqnA-2qjxA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  13
LEU A  16
ASN A  17
LEU A  20
GLN A  38
 None
 1.41A 2w8yB-2qjxA:
undetectable		 2w8yB-2qjxA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  13
LEU A  16
ASN A  17
LEU A  20
GLN A  38
 None
 1.42A 3d90A-2qjxA:
undetectable		 3d90A-2qjxA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  43
TRP A  15
SER A  42
ILE A  39
 None
 1.10A 3sfeB-2qjxA:
undetectable
3sfeC-2qjxA:
undetectable		 3sfeB-2qjxA:
19.51
3sfeC-2qjxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  13
LEU A  16
ASN A  17
LEU A  20
GLN A  38
 None
 1.33A 3zqtA-2qjxA:
undetectable		 3zqtA-2qjxA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2qjx PROTEIN BIM1
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 121
ALA A  34
GLN A  38
ILE A  39
 None
 1.18A 6f6sA-2qjxA:
undetectable
6f6sB-2qjxA:
undetectable		 6f6sA-2qjxA:
18.10
6f6sB-2qjxA:
20.16