SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qk2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 2qk2 LP04448P
(Drosophila
melanogaster) 		4 / 8 LEU A 394
ASN A 433
LEU A 439
LEU A 440
 None
 1.07A 1e7cA-2qk2A:
undetectable		 1e7cA-2qk2A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 12 TYR A 389
LEU A 437
LEU A 432
VAL A 475
LEU A 463
 None
 1.31A 1ie9A-2qk2A:
undetectable		 1ie9A-2qk2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 12 GLY A 464
VAL A 482
LEU A 444
SER A 443
LEU A 448
 None
 1.03A 1ya4C-2qk2A:
undetectable		 1ya4C-2qk2A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qk2 LP04448P
(Drosophila
melanogaster) 		4 / 5 LEU A 347
ALA A 387
ILE A 388
SER A 391
 None
 1.01A 2othA-2qk2A:
undetectable		 2othA-2qk2A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 12 PHE A 370
LEU A 347
LEU A 344
PHE A 355
ALA A 323
 None
 1.22A 2v0mC-2qk2A:
undetectable		 2v0mC-2qk2A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2qk2 LP04448P
(Drosophila
melanogaster) 		3 / 3 GLU A 297
GLU A 300
TRP A 292
 None
 1.04A 3hrdA-2qk2A:
undetectable
3hrdE-2qk2A:
undetectable
3hrdF-2qk2A:
undetectable		 3hrdA-2qk2A:
21.33
3hrdE-2qk2A:
21.33
3hrdF-2qk2A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 9 ILE A 385
SER A 360
SER A 393
LEU A 367
SER A 400
 None
 1.40A 3ijxB-2qk2A:
0.0
3ijxD-2qk2A:
0.0		 3ijxB-2qk2A:
25.27
3ijxD-2qk2A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 9 ALA A 497
GLY A 464
LEU A 424
LEU A 463
ILE A 420
 None
 1.47A 3wdmA-2qk2A:
undetectable		 3wdmA-2qk2A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 12 ALA A 474
ILE A 490
GLY A 464
LEU A 466
PRO A 429
 None
 1.00A 4xi3B-2qk2A:
undetectable		 4xi3B-2qk2A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 10 LEU A 394
LEU A 436
LEU A 466
THR A 427
LEU A 424
 None
 1.05A 4z91A-2qk2A:
undetectable
4z91B-2qk2A:
2.1
4z91C-2qk2A:
1.9
4z91D-2qk2A:
undetectable
4z91E-2qk2A:
3.2		 4z91A-2qk2A:
24.92
4z91B-2qk2A:
24.92
4z91C-2qk2A:
24.92
4z91D-2qk2A:
24.92
4z91E-2qk2A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 10 LEU A 466
THR A 427
LEU A 424
LEU A 394
LEU A 436
 None
 1.02A 4z91A-2qk2A:
undetectable
4z91B-2qk2A:
2.1
4z91C-2qk2A:
1.9
4z91D-2qk2A:
undetectable
4z91E-2qk2A:
3.2		 4z91A-2qk2A:
24.92
4z91B-2qk2A:
24.92
4z91C-2qk2A:
24.92
4z91D-2qk2A:
24.92
4z91E-2qk2A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2qk2 LP04448P
(Drosophila
melanogaster) 		5 / 10 THR A 427
LEU A 424
LEU A 394
LEU A 436
LEU A 466
 None
 1.04A 4z91A-2qk2A:
undetectable
4z91B-2qk2A:
2.1
4z91C-2qk2A:
1.9
4z91D-2qk2A:
undetectable
4z91E-2qk2A:
3.2		 4z91A-2qk2A:
24.92
4z91B-2qk2A:
24.92
4z91C-2qk2A:
24.92
4z91D-2qk2A:
24.92
4z91E-2qk2A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2qk2 LP04448P
(Drosophila
melanogaster) 		4 / 4 LEU A 367
ARG A 382
ILE A 385
PHE A 419
 None
 1.24A 5kirB-2qk2A:
undetectable		 5kirB-2qk2A:
18.82