SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2qk7 GAMMA-HEMOLYSIN
COMPONENT A
(Staphylococcus
aureus) 		4 / 6 ALA A  45
TYR A 111
TYR A  41
ILE A  92
 None
 1.26A 2dcfA-2qk7A:
undetectable		 2dcfA-2qk7A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qk7 GAMMA-HEMOLYSIN
COMPONENT A
(Staphylococcus
aureus) 		4 / 4 ILE A 135
GLN A 139
ILE A 123
LEU A 200
 None
 1.16A 3dzyD-2qk7A:
undetectable		 3dzyD-2qk7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 2qk7 GAMMA-HEMOLYSIN
COMPONENT A
(Staphylococcus
aureus) 		3 / 3 PRO A 182
PHE A 191
ALA A 238
 None
 0.54A 3itaD-2qk7A:
undetectable		 3itaD-2qk7A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qk7 GAMMA-HEMOLYSIN
COMPONENT A
(Staphylococcus
aureus) 		4 / 6 GLU A 147
THR A 144
GLN A  77
THR A 211
 None
 1.24A 4pfjB-2qk7A:
undetectable		 4pfjB-2qk7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2qk7 GAMMA-HEMOLYSIN
COMPONENT A
(Staphylococcus
aureus) 		5 / 11 GLN A  77
ASN A 258
VAL A 154
SER A  81
THR A 228
 None
 1.48A 5jh7B-2qk7A:
undetectable		 5jh7B-2qk7A:
20.57