SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 2qki COMPLEMENT C3
(Homo
sapiens) 		3 / 3 TRP C1583
ARG C1560
THR C1604
 None
 0.85A 1df7A-2qkiC:
undetectable		 1df7A-2qkiC:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 2qki COMPLEMENT C3
(Homo
sapiens) 		3 / 3 TRP C1605
ARG C1569
THR C1604
 None
 0.99A 1df7A-2qkiC:
undetectable		 1df7A-2qkiC:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2qki COMPLEMENT C3
(Homo
sapiens) 		3 / 3 ILE C1423
ILE C1380
THR C1421
 None
 0.39A 1rg7A-2qkiC:
undetectable		 1rg7A-2qkiC:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2qki COMPLEMENT C3
(Homo
sapiens) 		4 / 8 ILE C1366
PHE C1439
LEU C1399
ILE C1407
 None
 0.82A 2azxA-2qkiC:
undetectable		 2azxA-2qkiC:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qki COMPLEMENT C3
(Homo
sapiens) 		3 / 3 LYS C1335
ASP C1477
ASP C1535
 None
 0.98A 2br4A-2qkiC:
undetectable		 2br4A-2qkiC:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)		 2qki COMPLEMENT C3
(Homo
sapiens) 		4 / 4 GLY C1591
GLU C1592
ASP C1552
TYR C1598
 None
 1.36A 2yvlC-2qkiC:
undetectable		 2yvlC-2qkiC:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2qki COMPLEMENT C3
(Homo
sapiens) 		5 / 12 ALA C1376
ILE C1407
TYR C1425
ILE C1380
LEU C1437
 None
 1.11A 5h8tA-2qkiC:
undetectable		 5h8tA-2qkiC:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 2qki COMPLEMENT C3
(Homo
sapiens) 		5 / 12 MET C1385
ILE C1383
LEU C1381
PHE C1439
LEU C1341
 None
 1.09A 6b52A-2qkiC:
undetectable		 6b52A-2qkiC:
20.57