SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VID_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	2qkl	SPAC19A8.12 PROTEIN (Schizosaccharomy ces pombe)	4 / 5	SER B 16 TYR B 45 SER B 2 ASP B 13	None	1.49A	1vidA-2qklB: undetectable	1vidA-2qklB: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JZ0_B_CLYB900_1 (LINCOSAMIDE NUCLEOTIDYLTRANSFERA SE)	2qkl	SPAC19A8.12 PROTEIN (Schizosaccharomy ces pombe)	4 / 8	GLU B 83 GLU B 84 SER B 79 ILE B 20	None	0.88A	3jz0B-2qklB: undetectable	3jz0B-2qklB: 13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_P_TFPP202_1 (PROTEIN S100-A4)	2qkl	SPAC19A8.12 PROTEIN (Schizosaccharomy ces pombe)	5 / 12	ASP B 87 LEU B 75 LEU B 68 SER B 65 ILE B 20	None	1.23A	3ko0M-2qklB: undetectable 3ko0N-2qklB: undetectable 3ko0O-2qklB: undetectable 3ko0P-2qklB: undetectable	3ko0M-2qklB: 22.12 3ko0N-2qklB: 22.12 3ko0O-2qklB: 22.12 3ko0P-2qklB: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2qkl	SPAC19A8.12 PROTEIN (Schizosaccharomy ces pombe)	4 / 6	LYS B 2 GLN B 52 PHE B 48 LEU B 15	None	1.26A	6nmpC-2qklB: undetectable 6nmpJ-2qklB: undetectable	6nmpC-2qklB: 14.62 6nmpJ-2qklB: 19.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VID_A_SAMA301_1","CATECHOL O-METHYLTRANSFERASE","2qkl","SPAC19A8.12 PROTEIN","Schizosaccharomyces pombe",4,"SER B  16;TYR B  45;SER B   2;ASP B  13","None","1.49A","1vidA-2qklB:undetectable","1vidA-2qklB:18.96"],["3JZ0_B_CLYB900_1","LINCOSAMIDE NUCLEOTIDYLTRANSFERASE","2qkl","SPAC19A8.12 PROTEIN","Schizosaccharomyces pombe",4,"GLU B  83;GLU B  84;SER B  79;ILE B  20","None","0.88A","3jz0B-2qklB:undetectable","3jz0B-2qklB:13.75"],["3KO0_P_TFPP202_1","PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4","2qkl","SPAC19A8.12 PROTEIN","Schizosaccharomyces pombe",5,"ASP B  87;LEU B  75;LEU B  68;SER B  65;ILE B  20","None","1.23A","3ko0M-2qklB:undetectable;3ko0N-2qklB:undetectable;3ko0O-2qklB:undetectable;3ko0P-2qklB:undetectable","3ko0M-2qklB:22.12;3ko0N-2qklB:22.12;3ko0O-2qklB:22.12;3ko0P-2qklB:22.12"],["6NMP_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2qkl","SPAC19A8.12 PROTEIN","Schizosaccharomyces pombe",4,"LYS B   2;GLN B  52;PHE B  48;LEU B  15","None","1.26A","6nmpC-2qklB:undetectable;6nmpJ-2qklB:undetectable","6nmpC-2qklB:14.62;6nmpJ-2qklB:19.78"]]