SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qko'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 8 ILE A  61
VAL A  32
GLY A  58
LEU A 119
 None
 0.97A 1dzmA-2qkoA:
undetectable		 1dzmA-2qkoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 8 VAL A  18
GLY A  41
THR A  42
ALA A  43
 None
 0.80A 2a1hA-2qkoA:
undetectable
2a1hB-2qkoA:
undetectable		 2a1hA-2qkoA:
20.05
2a1hB-2qkoA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 LEU A  19
GLY A  26
GLY A  23
ALA A  31
THR A  28
 None
 1.14A 3dh0B-2qkoA:
undetectable		 3dh0B-2qkoA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 LEU A 109
ALA A  31
ALA A  15
VAL A  18
GLY A  26
 None
 0.97A 4hfpD-2qkoA:
undetectable		 4hfpD-2qkoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 LEU A 109
ALA A  31
ALA A  15
VAL A  18
GLY A  26
 None
 0.96A 4rn6B-2qkoA:
undetectable		 4rn6B-2qkoA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 6 ASP A 175
ARG A 178
LEU A 179
ASP A 182
 None
 0.79A 5tdzA-2qkoA:
undetectable		 5tdzA-2qkoA:
21.19