SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 2qkq EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		3 / 3 TRP A 915
ALA A 963
VAL A 965
 None
 0.84A 2izqA-2qkqA:
undetectable
2izqB-2qkqA:
undetectable		 2izqA-2qkqA:
12.12
2izqB-2qkqA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 2qkq EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		3 / 3 ALA A 963
VAL A 965
TRP A 915
 None
 0.84A 3l8lA-2qkqA:
undetectable
3l8lB-2qkqA:
undetectable		 3l8lA-2qkqA:
12.12
3l8lB-2qkqA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 2qkq EPHRIN TYPE-B
RECEPTOR 4
(Homo
sapiens) 		3 / 3 ALA A 963
VAL A 965
TRP A 915
 None
 0.85A 3l8lC-2qkqA:
undetectable
3l8lD-2qkqA:
undetectable		 3l8lC-2qkqA:
12.12
3l8lD-2qkqA:
9.64