SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ql7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 2ql7 CASPASE-7
(Homo
sapiens) 		4 / 6 LEU A 180
LEU A  97
LEU A 104
ILE A  72
 None
 1.01A 1z95A-2ql7A:
undetectable		 1z95A-2ql7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 2ql7 CASPASE-7
(Homo
sapiens) 		5 / 10 PHE A 182
ALA A  96
PHE A 101
PHE A 106
LEU A 104
 None
 1.37A 3a3yA-2ql7A:
2.5		 3a3yA-2ql7A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 2ql7 CASPASE-7
(Homo
sapiens) 		5 / 12 MET A 119
LEU A 123
ILE A 183
ILE A 150
LEU A 142
 None
 1.01A 4j24C-2ql7A:
undetectable		 4j24C-2ql7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 2ql7 CASPASE-7
(Homo
sapiens) 		5 / 12 MET A 119
LEU A 123
ILE A 150
LEU A 162
LEU A 142
 None
 1.20A 4j24D-2ql7A:
undetectable		 4j24D-2ql7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2ql7 CASPASE-7
(Homo
sapiens) 		5 / 12 MET A 119
LEU A 123
ILE A 183
ILE A 150
LEU A 142
 None
 1.02A 4j26B-2ql7A:
undetectable		 4j26B-2ql7A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 2ql7 CASPASE-7
(Homo
sapiens) 		5 / 12 MET A 119
LEU A 123
ILE A 150
LEU A 162
LEU A 142
 None
 1.22A 5toaB-2ql7A:
undetectable		 5toaB-2ql7A:
21.43