SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ql8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		5 / 11 ILE A 116
GLY A  76
GLU A  67
THR A 113
GLU A  60
 None
 1.35A 2fn1B-2ql8A:
undetectable		 2fn1B-2ql8A:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		5 / 7 ALA A  61
THR A  62
ALA A  65
ARG A 119
PRO A 121
 BEZ  A 143 ( 4.0A)
BEZ  A 143 (-3.4A)
BEZ  A 143 (-3.6A)
BEZ  A 143 (-3.9A)
None
 0.00A 2ql8A-2ql8A:
24.6
2ql8B-2ql8A:
23.4		 2ql8A-2ql8A:
100.00
2ql8B-2ql8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		4 / 6 THR A  62
ALA A  65
ARG A 119
PRO A 121
 BEZ  A 143 (-3.4A)
BEZ  A 143 (-3.6A)
BEZ  A 143 (-3.9A)
None
 0.15A 2ql8A-2ql8A:
24.6
2ql8B-2ql8A:
23.4		 2ql8A-2ql8A:
100.00
2ql8B-2ql8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		4 / 8 SER A  54
VAL A 122
LEU A 126
ALA A  97
 None
 0.99A 3ax7A-2ql8A:
undetectable		 3ax7A-2ql8A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		5 / 9 THR A 136
LEU A  63
GLY A  76
THR A  75
VAL A 104
 None
 1.42A 4c9kA-2ql8A:
undetectable		 4c9kA-2ql8A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ql8 PUTATIVE REDOX
PROTEIN
(Lactobacillus
paracasei) 		5 / 9 VAL A  95
LEU A  94
LEU A  51
GLY A 130
LEU A 126
 None
 1.01A 4rs0A-2ql8A:
4.0		 4rs0A-2ql8A:
14.94