SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		4 / 8 ILE A  44
PHE A  31
LEU A  95
ALA A  63
 None
 0.84A 3hrdA-2qlcA:
undetectable
3hrdB-2qlcA:
undetectable		 3hrdA-2qlcA:
16.89
3hrdB-2qlcA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		4 / 6 ALA A  87
ASP A  88
LEU A  49
THR A  48
 None
 1.00A 3rozA-2qlcA:
undetectable		 3rozA-2qlcA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		3 / 3 LYS A  16
GLU A  13
TRP A 117
 None
 0.73A 3v4tH-2qlcA:
undetectable		 3v4tH-2qlcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		5 / 12 ILE A 111
HIS A  77
GLY A 113
HIS A 109
ALA A   8
 None
 1.21A 5igyA-2qlcA:
undetectable		 5igyA-2qlcA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		5 / 10 ILE A  71
LEU A  32
HIS A  77
ILE A 111
ASN A  76
 None
 1.30A 5vkqA-2qlcA:
undetectable
5vkqD-2qlcA:
undetectable		 5vkqA-2qlcA:
5.99
5vkqD-2qlcA:
5.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		5 / 10 HIS A  77
ILE A 111
ASN A  76
ILE A  71
LEU A  32
 None
 1.31A 5vkqA-2qlcA:
undetectable
5vkqB-2qlcA:
undetectable		 5vkqA-2qlcA:
5.99
5vkqB-2qlcA:
5.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2qlc DNA REPAIR PROTEIN
RADC HOMOLOG
(Chlorobaculum
tepidum) 		5 / 10 HIS A  77
ILE A 111
ASN A  76
ILE A  71
LEU A  32
 None
 1.31A 5vkqC-2qlcA:
undetectable
5vkqD-2qlcA:
undetectable		 5vkqC-2qlcA:
5.99
5vkqD-2qlcA:
5.99