SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 572
VAL A 518
MET A 519
LEU A 626
 None
 0.96A 1hk3A-2qlvA:
undetectable		 1hk3A-2qlvA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
PROTEIN SIP2
(Saccharomyces
cerevisiae) 		4 / 6 VAL B 382
VAL A 582
ILE A 623
MET A 519
 None
 1.08A 1iepA-2qlvB:
undetectable		 1iepA-2qlvB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		4 / 6 TYR B 323
GLU B 320
PRO B 316
VAL B 312
 None
 1.42A 1q13A-2qlvB:
undetectable		 1q13A-2qlvB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 218
ASP B 220
GLY B 174
LEU B 192
TYR B 178
 None
 0.93A 1rjdC-2qlvB:
undetectable		 1rjdC-2qlvB:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		5 / 12 LEU C 318
LEU C 314
LEU C 310
LEU C 132
MET C 284
 None
 1.35A 1sqnA-2qlvC:
undetectable		 1sqnA-2qlvC:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 206
GLY B 181
ILE B 218
VAL B 204
ILE B 168
 None
 0.93A 2avvE-2qlvB:
undetectable		 2avvE-2qlvB:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		5 / 12 ASP B 220
PHE B 202
GLY B 174
GLY B 191
VAL B 204
 None
 1.24A 2fqyA-2qlvB:
undetectable		 2fqyA-2qlvB:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
(Saccharomyces
cerevisiae) 		4 / 5 SER A 513
ASP A 517
PRO A 515
SER A 511
 None
 1.34A 2hdnA-2qlvA:
undetectable
2hdnB-2qlvA:
undetectable
2hdnD-2qlvA:
undetectable		 2hdnA-2qlvA:
11.24
2hdnB-2qlvA:
19.29
2hdnD-2qlvA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
(Saccharomyces
cerevisiae) 		4 / 5 SER A 511
SER A 513
ASP A 517
PRO A 515
 None
 1.32A 2hdnB-2qlvA:
undetectable
2hdnC-2qlvA:
undetectable
2hdnD-2qlvA:
undetectable		 2hdnB-2qlvA:
19.29
2hdnC-2qlvA:
11.24
2hdnD-2qlvA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
PROTEIN SIP2
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 381
LEU A 618
LEU A 526
LEU A 626
THR B 383
 None
 1.43A 2oaxA-2qlvB:
undetectable		 2oaxA-2qlvB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		5 / 12 SER C 221
ARG C 294
GLY C 306
ASP C 197
ASN C 192
 None
 1.46A 3a25A-2qlvC:
undetectable		 3a25A-2qlvC:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 8 HIS A 478
ASN C 234
ILE C 225
ARG C 264
 None
 1.29A 3ccfB-2qlvA:
undetectable		 3ccfB-2qlvA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		5 / 12 THR C 309
ASP C 312
THR C 195
SER C 221
PRO C 224
 None
 0.87A 3kpbC-2qlvC:
9.3		 3kpbC-2qlvC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		6 / 12 THR C 309
ASP C 312
THR C 195
SER C 221
VAL C 223
PRO C 224
 None
 1.06A 3kpdC-2qlvC:
8.7		 3kpdC-2qlvC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
PROTEIN SIP2
(Saccharomyces
cerevisiae) 		4 / 7 VAL B 382
VAL A 582
ILE A 623
MET A 519
 None
 1.06A 3mssB-2qlvB:
undetectable		 3mssB-2qlvB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		4 / 6 ARG B 169
GLN B 171
PHE B 217
LEU B 192
 None
 1.27A 3tgvB-2qlvB:
undetectable		 3tgvB-2qlvB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2qlv PROTEIN SIP2
(Saccharomyces
cerevisiae) 		4 / 6 ARG B 169
GLN B 171
PHE B 217
LEU B 192
 None
 1.32A 3tgvD-2qlvB:
undetectable		 3tgvD-2qlvB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		4 / 7 VAL C  11
SER C 281
GLN C  15
ASP C 190
 None
 1.21A 4hxyB-2qlvC:
undetectable		 4hxyB-2qlvC:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		4 / 6 ARG C 294
GLU C 269
ARG C 264
ASP C 240
 None
 1.36A 4kcnA-2qlvC:
undetectable		 4kcnA-2qlvC:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		4 / 6 ARG C 294
GLU C 269
ARG C 264
ASP C 240
 None
 1.32A 4kcnB-2qlvC:
undetectable		 4kcnB-2qlvC:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		5 / 11 SER C 125
THR C 123
SER C 142
GLU C 113
GLY C  77
 None
 1.40A 4qb9F-2qlvC:
undetectable		 4qb9F-2qlvC:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 515
VAL A 518
ILE A 522
VAL A 582
 None
 0.66A 5bmvC-2qlvA:
undetectable		 5bmvC-2qlvA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2qlv NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae) 		3 / 3 ASN C 286
TYR C 272
CYH C 274
 None
 0.93A 5lsuB-2qlvC:
undetectable		 5lsuB-2qlvC:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
PROTEIN SIP2
NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 8 ILE C  42
GLN B 406
TYR A 613
VAL C 164
 None
 1.05A 5vlmF-2qlvC:
undetectable		 5vlmF-2qlvC:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2qlv PROTEIN SIP2
NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 5 TYR B 242
ARG B 214
THR B 233
LEU C  35
 None
 1.38A 5x1fW-2qlvB:
undetectable		 5x1fW-2qlvB:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 586
GLN A 571
ILE A 522
TYR A 523
LEU A 526
 None
 1.05A 5y2tB-2qlvA:
undetectable		 5y2tB-2qlvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE
NUCLEAR PROTEIN SNF4
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 470
VAL C 235
ASP C 240
PHE C 268
SER A 473
 None
 1.49A 6b50A-2qlvA:
undetectable		 6b50A-2qlvA:
22.75