SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 11 ALA A 161
GLY A 165
GLY A 146
ILE A 147
VAL A 143
 None
None
MG  A1007 ( 4.2A)
None
None
 1.17A 1pg2A-2qm1A:
undetectable		 1pg2A-2qm1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 ILE A   8
ILE A  68
THR A  72
 None
 0.50A 1rg7A-2qm1A:
undetectable		 1rg7A-2qm1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 ILE A 298
ILE A 265
THR A 296
 None
 0.61A 1rg7A-2qm1A:
undetectable		 1rg7A-2qm1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 8 ALA A 119
LEU A 120
GLY A 311
GLY A  71
 None
 0.83A 1rukH-2qm1A:
undetectable
1rukL-2qm1A:
undetectable		 1rukH-2qm1A:
19.27
1rukL-2qm1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 10 ILE A   6
ALA A 316
GLN A 318
ALA A 110
ILE A  55
 None
 1.16A 2aclC-2qm1A:
undetectable		 2aclC-2qm1A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 ALA A 110
ASN A 113
ILE A  47
ILE A  43
THR A  72
 None
 1.17A 2bjfA-2qm1A:
undetectable		 2bjfA-2qm1A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 ALA A 312
ASN A 113
ILE A  15
ILE A  43
THR A  72
 None
 1.31A 2bjfA-2qm1A:
undetectable		 2bjfA-2qm1A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 5 LEU A 276
ARG A 277
ALA A 272
ILE A 265
 None
 1.04A 2qhfA-2qm1A:
undetectable		 2qhfA-2qm1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 8 VAL A  26
GLY A 311
GLY A  69
ALA A 313
GLU A 306
 None
 1.38A 3aruA-2qm1A:
undetectable		 3aruA-2qm1A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 10 ALA A 229
VAL A 239
ALA A 213
ILE A 214
PHE A 235
 None
 1.14A 3fl9A-2qm1A:
undetectable		 3fl9A-2qm1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 10 ALA A 229
VAL A 239
ALA A 213
ILE A 214
PHE A 235
 None
 1.16A 3fl9F-2qm1A:
undetectable		 3fl9F-2qm1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 GLY A 255
THR A 257
ASN A 253
 None
 0.70A 3v4tD-2qm1A:
undetectable		 3v4tD-2qm1A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 GLY A 267
GLY A 140
ILE A 137
VAL A 143
ALA A 271
 None
 1.17A 4a6dA-2qm1A:
undetectable		 4a6dA-2qm1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 GLY A 267
GLY A 140
ILE A 137
VAL A 143
ALA A 271
 None
 1.16A 4a6eA-2qm1A:
undetectable		 4a6eA-2qm1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 6 THR A  14
GLY A  12
ILE A  36
LEU A  10
 None
 1.18A 4ac9C-2qm1A:
undetectable		 4ac9C-2qm1A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 6 THR A  14
GLY A  12
ILE A  36
LEU A  10
 None
 1.14A 4acaC-2qm1A:
undetectable		 4acaC-2qm1A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 7 GLY A 248
THR A 251
ILE A 265
LEU A 276
 None
 0.73A 4ejjD-2qm1A:
undetectable		 4ejjD-2qm1A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 7 GLY A 144
GLY A 145
ASN A 116
GLU A 185
 None
MG  A1007 (-4.6A)
MG  A1007 (-2.8A)
None
 1.04A 4fgkB-2qm1A:
undetectable		 4fgkB-2qm1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 5 GLY A 144
GLY A 145
ASN A 116
GLU A 185
 None
MG  A1007 (-4.6A)
MG  A1007 (-2.8A)
None
 1.14A 4fglC-2qm1A:
undetectable		 4fglC-2qm1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 GLN A  95
THR A  93
THR A  92
 None
 0.72A 4fu9A-2qm1A:
undetectable		 4fu9A-2qm1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 GLN A  95
THR A  93
THR A  92
 None
 0.72A 4fufA-2qm1A:
undetectable		 4fufA-2qm1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 ASP A 114
VAL A 143
ASN A  88
 None
 0.68A 4lmnA-2qm1A:
undetectable		 4lmnA-2qm1A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 LYS A 180
ARG A 195
VAL A 187
 ZN  A1002 ( 4.5A)
None
None
 0.94A 4x3uA-2qm1A:
undetectable
4x3uB-2qm1A:
undetectable		 4x3uA-2qm1A:
12.50
4x3uB-2qm1A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.35A 5i1nC-2qm1A:
undetectable		 5i1nC-2qm1A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 ALA A 197
GLY A 182
PHE A 174
SER A 188
GLY A 192
 None
 1.08A 5i75A-2qm1A:
undetectable		 5i75A-2qm1A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		4 / 8 LEU A  10
VAL A  44
LEU A 111
ILE A 101
 None
 1.01A 5v0vA-2qm1A:
1.9		 5v0vA-2qm1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 2qm1 GLUCOKINASE
(Enterococcus
faecalis) 		5 / 12 GLY A 192
VAL A 193
PHE A 226
GLY A 267
GLY A 266
 None
 1.20A 6brdB-2qm1A:
undetectable		 6brdB-2qm1A:
14.20