SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU B 466
VAL B 468
SER B 384
SER B 560
VAL B 487
 None
 1.34A 1db1A-2qm6B:
undetectable		 1db1A-2qm6B:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 ILE B 476
GLY B 473
GLY B 472
THR B 396
ASN B 400
 None
GLU  B   1 (-3.6A)
GLU  B   1 (-3.6A)
None
GLU  B   1 (-3.5A)
 1.04A 1likA-2qm6B:
undetectable		 1likA-2qm6B:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		4 / 8 TYR B 433
ARG B 475
GLY B 473
PRO B 471
 GLU  B   1 (-4.3A)
None
GLU  B   1 (-3.6A)
GLU  B   1 ( 4.8A)
 1.07A 2ys6A-2qm6B:
undetectable		 2ys6A-2qm6B:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 ASN B 418
ASP B 422
ARG B 513
 None
GLU  B   1 (-2.9A)
None
 0.84A 3k13A-2qm6B:
undetectable		 3k13A-2qm6B:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		5 / 12 ILE B 457
VAL B 458
GLY B 469
LEU B 466
LEU B 481
 None
 1.04A 3mb5A-2qm6B:
undetectable		 3mb5A-2qm6B:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 540
HIS B 504
GLY B 473
 None
None
GLU  B   1 (-3.6A)
 0.80A 5gwzB-2qm6B:
undetectable		 5gwzB-2qm6B:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 505
GLN B 506
ARG B 513
 None
 1.11A 5m35B-2qm6B:
undetectable		 5m35B-2qm6B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 505
GLN B 506
ARG B 513
 None
 1.06A 5m36A-2qm6B:
undetectable		 5m36A-2qm6B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 505
GLN B 506
ARG B 513
 None
 1.10A 6fn9A-2qm6B:
undetectable		 6fn9A-2qm6B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 505
GLN B 506
ARG B 513
 None
 1.13A 6fnaB-2qm6B:
undetectable		 6fnaB-2qm6B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE
(Helicobacter
pylori) 		3 / 3 MET B 505
GLN B 506
ARG B 513
 None
 1.10A 6fnbA-2qm6B:
undetectable		 6fnbA-2qm6B:
21.40