SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
4 / 5 LEU A 149
LEU A 147
LEU A 212
GLY A 204
None
0.94A 1a4lC-2qmmA:
undetectable
1a4lC-2qmmA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
4 / 8 PHE A 239
ILE A 219
HIS A 282
LEU A 283
None
0.89A 1fslA-2qmmA:
undetectable
1fslA-2qmmA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 11 GLY A 242
GLY A 246
SER A 269
LEU A 270
ALA A 272
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.1A)
SAM  A 301 (-4.5A)
SAM  A 301 ( 4.0A)
0.58A 1x7pA-2qmmA:
10.0
1x7pB-2qmmA:
10.5
1x7pA-2qmmA:
23.13
1x7pB-2qmmA:
23.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
9 / 9 LEU A 221
GLU A 223
ILE A 241
GLY A 242
GLY A 246
SER A 264
SER A 266
LEU A 270
CYH A 275
SAM  A 301 (-4.3A)
SAM  A 301 (-3.5A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.1A)
0.02A 2qmmA-2qmmA:
41.2
2qmmA-2qmmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
10 / 11 LEU A 221
GLU A 223
ILE A 241
GLY A 242
GLY A 246
SER A 264
LEU A 265
SER A 266
LEU A 270
CYH A 275
SAM  A 301 (-4.3A)
SAM  A 301 (-3.5A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.1A)
0.20A 2qmmA-2qmmA:
41.2
2qmmB-2qmmA:
39.0
2qmmA-2qmmA:
100.00
2qmmB-2qmmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 11 SER A 269
ILE A 241
GLY A 242
GLY A 246
LEU A 270
CYH A 275
SAM  A 301 (-4.1A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.1A)
1.18A 2qmmA-2qmmA:
41.2
2qmmB-2qmmA:
39.0
2qmmA-2qmmA:
100.00
2qmmB-2qmmA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 10 LEU A 221
GLY A 242
LEU A 265
SER A 266
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
0.54A 2v3kA-2qmmA:
14.7
2v3kA-2qmmA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
4 / 6 LEU A 149
VAL A 101
VAL A 254
VAL A 255
None
1.00A 2z97A-2qmmA:
undetectable
2z97A-2qmmA:
18.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
8 / 9 LEU A 221
ILE A 241
GLY A 242
SER A 264
LEU A 265
SER A 266
LEU A 270
CYH A 275
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.1A)
0.36A 3ai9X-2qmmA:
31.2
3ai9X-2qmmA:
43.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 6 LEU A 221
GLY A 242
LEU A 265
SER A 266
CYH A 275
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-3.1A)
0.33A 3aiaA-2qmmA:
31.8
3aiaA-2qmmA:
44.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 12 VAL A 142
ASP A 141
ARG A 285
PRO A 237
LEU A 233
None
1.28A 3j6pB-2qmmA:
undetectable
3j6pB-2qmmA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 12 LEU A 221
GLY A 242
GLY A 246
SER A 269
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.1A)
SAM  A 301 (-4.5A)
0.94A 3nk7B-2qmmA:
10.7
3nk7B-2qmmA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 10 LEU A 221
ILE A 241
GLY A 242
GLY A 246
SER A 266
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.2A)
0.69A 4fakA-2qmmA:
6.9
4fakA-2qmmA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
4 / 7 GLU A 164
ILE A 160
ARG A 139
ILE A 138
None
0.48A 4xumA-2qmmA:
undetectable
4xumA-2qmmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 9 LEU A 221
ILE A 241
GLY A 242
GLY A 246
LEU A 265
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.5A)
0.73A 5o96A-2qmmA:
10.9
5o96B-2qmmA:
11.2
5o96A-2qmmA:
25.40
5o96B-2qmmA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 11 LEU A 221
GLY A 242
GLY A 246
LEU A 265
GLU A 273
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.4A)
None
0.77A 5o96G-2qmmA:
11.2
5o96G-2qmmA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 11 LEU A 221
GLY A 242
GLY A 246
SER A 264
LEU A 265
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.4A)
1.03A 5o96G-2qmmA:
11.2
5o96G-2qmmA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
7 / 12 LEU A 221
ILE A 241
GLY A 242
GLY A 246
SER A 264
LEU A 265
SER A 266
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
0.61A 5twjA-2qmmA:
6.6
5twjA-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
7 / 12 LEU A 221
ILE A 241
GLY A 242
GLY A 246
SER A 264
SER A 266
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
0.46A 5twjA-2qmmA:
6.6
5twjA-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 10 LEU A 221
ILE A 241
GLY A 242
GLY A 246
LEU A 265
SER A 266
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
0.66A 5twjB-2qmmA:
6.4
5twjB-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 10 LEU A 221
ILE A 241
GLY A 242
GLY A 246
SER A 266
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
0.50A 5twjB-2qmmA:
6.4
5twjB-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 12 LEU A 221
ILE A 241
GLY A 242
SER A 264
LEU A 265
SER A 266
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
0.56A 5twjC-2qmmA:
7.4
5twjC-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
6 / 12 LEU A 221
ILE A 241
GLY A 242
SER A 264
SER A 266
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
0.46A 5twjC-2qmmA:
7.4
5twjC-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
7 / 11 LEU A 221
ILE A 241
GLY A 242
GLY A 246
LEU A 265
SER A 266
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-4.4A)
SAM  A 301 (-4.2A)
SAM  A 301 (-4.5A)
0.66A 5twjD-2qmmA:
7.4
5twjD-2qmmA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
2qmm UPF0217 PROTEIN
AF_1056

(Archaeoglobus
fulgidus)
5 / 12 LEU A 221
GLY A 242
GLY A 246
SER A 264
LEU A 270
SAM  A 301 (-4.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.4A)
SAM  A 301 (-4.5A)
0.78A 5zhmB-2qmmA:
8.4
5zhmB-2qmmA:
23.00