SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 4 LEU A 163
SER A   5
LEU A 136
LEU A 168
 None
 1.11A 1yajA-2qmoA:
undetectable		 1yajA-2qmoA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 6 LEU A 121
ASN A 130
LEU A 138
LEU A 168
 None
 0.85A 1z95A-2qmoA:
undetectable		 1z95A-2qmoA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		5 / 12 LEU A  99
LEU A 138
GLY A 117
SER A  49
ALA A  51
 None
 1.02A 2br4C-2qmoA:
undetectable		 2br4C-2qmoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 8 LEU A 121
ALA A  80
THR A  39
ILE A  37
 None
 0.77A 3jusB-2qmoA:
undetectable		 3jusB-2qmoA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 7 LEU A  33
ARG A  18
THR A  14
ALA A  17
 None
None
CL  A 302 (-4.0A)
None
 1.10A 3mbgA-2qmoA:
undetectable
3mbgB-2qmoA:
undetectable		 3mbgA-2qmoA:
16.97
3mbgB-2qmoA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 5 GLU A  38
GLY A  40
TYR A  75
GLU A  88
 None
 1.35A 3w9tA-2qmoA:
undetectable		 3w9tA-2qmoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 5 GLU A  38
GLY A  40
TYR A  75
GLU A  88
 None
 1.35A 3w9tC-2qmoA:
undetectable		 3w9tC-2qmoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 5 GLU A  38
GLY A  40
TYR A  75
GLU A  88
 None
 1.34A 3w9tD-2qmoA:
undetectable		 3w9tD-2qmoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 5 GLU A  38
GLY A  40
TYR A  75
GLU A  88
 None
 1.35A 3w9tG-2qmoA:
undetectable		 3w9tG-2qmoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		5 / 12 ALA A 118
GLY A 119
GLY A 120
ILE A 125
ASN A 130
 None
 1.08A 4obwB-2qmoA:
undetectable		 4obwB-2qmoA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 7 LEU A 121
ASN A 130
LEU A 138
LEU A 168
 None
 0.86A 4okwA-2qmoA:
undetectable		 4okwA-2qmoA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		4 / 6 LEU A 168
ALA A 140
LEU A 136
VAL A 115
 None
 1.21A 5a6iA-2qmoA:
undetectable		 5a6iA-2qmoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2qmo DETHIOBIOTIN
SYNTHETASE
(Helicobacter
pylori) 		3 / 3 TYR A  23
ALA A 216
LEU A 217
 None
 0.56A 6ag0C-2qmoA:
undetectable		 6ag0C-2qmoA:
18.69