SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 2qnd FMR1 PROTEIN
(Homo
sapiens) 		4 / 6 SER A 128
ILE A 129
ALA A  67
ALA A  18
 None
 0.93A 1w0gA-2qndA:
undetectable		 1w0gA-2qndA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2qnd FMR1 PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  92
ASP A 137
VAL A  73
ILE A 103
PHE A 122
 None
 1.33A 5tiwB-2qndA:
undetectable		 5tiwB-2qndA:
17.39