SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 6 PHE A  42
ASP A 110
TYR A  20
PRO A   6
 None
 1.31A 3jqaA-2qntA:
undetectable		 3jqaA-2qntA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 6 PHE A  42
ASP A 110
TYR A  20
PRO A   6
 None
 1.35A 3jqaB-2qntA:
undetectable		 3jqaB-2qntA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 6 PHE A  42
ASP A 110
TYR A  20
PRO A   6
 None
 1.31A 3jqaC-2qntA:
undetectable		 3jqaC-2qntA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 6 PHE A  42
ASP A 110
TYR A  20
PRO A   6
 None
 1.29A 3jqaD-2qntA:
undetectable		 3jqaD-2qntA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 5 ASN A  69
GLU A  51
TYR A  65
PHE A   9
 None
 1.42A 4twdC-2qntA:
0.0
4twdD-2qntA:
0.0		 4twdC-2qntA:
17.61
4twdD-2qntA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2qnt UNCHARACTERIZED
PROTEIN ATU1872
(Agrobacterium
fabrum) 		4 / 6 ASN A  69
GLU A  51
TYR A  65
PHE A   9
 None
 1.47A 4twdG-2qntA:
undetectable
4twdH-2qntA:
undetectable		 4twdG-2qntA:
17.61
4twdH-2qntA:
17.61