SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 107
GLY A 103
GLY A 102
LEU A 104
 None
 0.62A 1qzzA-2qnuA:
undetectable		 1qzzA-2qnuA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 172
ALA A 171
ILE A 148
LEU A 157
ARG A 159
 None
 1.14A 1tw4A-2qnuA:
undetectable		 1tw4A-2qnuA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  33
LEU A 201
ILE A  62
ALA A  92
PHE A 210
 None
 0.95A 2gj5A-2qnuA:
undetectable		 2gj5A-2qnuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 145
PRO A 146
GLN A 174
 None
 0.31A 4oltB-2qnuA:
undetectable		 4oltB-2qnuA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 145
PRO A 146
GLN A 174
 None
 0.37A 4qwpB-2qnuA:
undetectable		 4qwpB-2qnuA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  99
LEU A  95
ALA A 170
GLY A 103
PRO A 142
 None
 1.29A 5jglA-2qnuA:
undetectable		 5jglA-2qnuA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  99
LEU A  95
ALA A 170
GLY A 103
PRO A 142
 None
 1.32A 5jglB-2qnuA:
undetectable		 5jglB-2qnuA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		3 / 3 TYR A  86
SER A  79
TRP A  48
 None
MLZ  A   9 ( 2.6A)
None
 1.07A 5n8jB-2qnuA:
undetectable		 5n8jB-2qnuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		4 / 5 TYR A  52
GLN A  41
GLY A  14
ILE A  80
 None
None
None
ACT  A 228 ( 4.6A)
 1.29A 6debB-2qnuA:
undetectable		 6debB-2qnuA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 2qnu UNCHARACTERIZED
PROTEIN PA0076
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  21
LEU A  67
GLY A  68
ILE A  62
ALA A  63
 None
 1.32A 6qxsD-2qnuA:
undetectable		 6qxsD-2qnuA:
20.12