SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qo4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 LEU A  18
ALA A  31
ASP A  74
HIS A  98
ARG A 120
 CHD  A 130 ( 4.7A)
CHD  A 130 ( 3.8A)
GOL  A 145 ( 2.8A)
IPA  A 140 (-3.7A)
CHD  A 130 (-3.4A)
 0.69A 1tw4A-2qo4A:
21.6		 1tw4A-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 11 ASN A  60
THR A  72
VAL A  82
HIS A  98
GLN A 100
 IPA  A 141 ( 4.7A)
GOL  A 145 (-3.2A)
None
IPA  A 140 (-3.7A)
IPA  A 142 (-3.5A)
 0.78A 1tw4A-2qo4A:
21.6		 1tw4A-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 TYR A  14
LEU A  18
MET A  73
HIS A  98
ARG A 120
 None
CHD  A 130 ( 4.7A)
None
IPA  A 140 (-3.7A)
CHD  A 130 (-3.4A)
 0.98A 1tw4B-2qo4A:
21.5		 1tw4B-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 TYR A  14
LEU A  18
THR A  53
MET A  73
ARG A 120
 None
CHD  A 130 ( 4.7A)
CHD  A 130 ( 4.1A)
None
CHD  A 130 (-3.4A)
 0.91A 1tw4B-2qo4A:
21.5		 1tw4B-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_B_CHDB1131_0
(FATTY ACID-BINDING
PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 10 ASN A  60
THR A  72
VAL A  82
HIS A  98
GLN A 100
 IPA  A 141 ( 4.7A)
GOL  A 145 (-3.2A)
None
IPA  A 140 (-3.7A)
IPA  A 142 (-3.5A)
 0.83A 1tw4B-2qo4A:
21.5		 1tw4B-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		7 / 12 PHE A  17
ASN A  60
PHE A  62
ILE A  70
VAL A  82
HIS A  98
LEU A 111
 None
IPA  A 141 ( 4.7A)
IPA  A 142 ( 4.4A)
IPA  A 141 ( 4.5A)
None
IPA  A 140 (-3.7A)
CHD  A 130 ( 4.9A)
 1.05A 2ft9A-2qo4A:
20.7		 2ft9A-2qo4A:
69.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 11 TYR A  14
LEU A  18
THR A  53
PRO A  54
LEU A 111
 None
CHD  A 130 ( 4.7A)
CHD  A 130 ( 4.1A)
None
CHD  A 130 ( 4.9A)
 0.95A 2ft9A-2qo4A:
20.7		 2ft9A-2qo4A:
69.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		6 / 12 TYR A  14
LEU A  18
ALA A  31
THR A  53
ASP A  74
HIS A  98
 None
CHD  A 130 ( 4.7A)
CHD  A 130 ( 3.8A)
CHD  A 130 ( 4.1A)
GOL  A 145 ( 2.8A)
IPA  A 140 (-3.7A)
 0.87A 2jn3A-2qo4A:
21.0		 2jn3A-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 7 PHE A  17
LEU A  23
PRO A  36
GLU A 109
ARG A 120
 None
CHD  A 130 ( 4.6A)
None
None
CHD  A 130 (-3.4A)
 0.72A 2jn3A-2qo4A:
21.0		 2jn3A-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 PHE A  62
ILE A  70
THR A  72
VAL A  82
HIS A  98
 IPA  A 142 ( 4.4A)
IPA  A 141 ( 4.5A)
GOL  A 145 (-3.2A)
None
IPA  A 140 (-3.7A)
 0.67A 2jn3A-2qo4A:
21.0		 2jn3A-2qo4A:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		7 / 12 LEU A  23
ILE A  21
ALA A  31
VAL A  34
THR A  72
MET A  73
PHE A  96
 CHD  A 130 ( 4.6A)
GOL  A 145 ( 4.8A)
CHD  A 130 ( 3.8A)
CHD  A 130 ( 4.8A)
GOL  A 145 (-3.2A)
None
CHD  A 130 ( 4.6A)
 1.41A 2qo4A-2qo4A:
27.7		 2qo4A-2qo4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		12 / 12 TYR A  14
LEU A  18
ILE A  21
ALA A  31
VAL A  34
THR A  72
MET A  73
ASP A  74
PHE A  96
HIS A  98
MET A 118
ARG A 120
 None
CHD  A 130 ( 4.7A)
GOL  A 145 ( 4.8A)
CHD  A 130 ( 3.8A)
CHD  A 130 ( 4.8A)
GOL  A 145 (-3.2A)
None
GOL  A 145 ( 2.8A)
CHD  A 130 ( 4.6A)
IPA  A 140 (-3.7A)
CHD  A 130 ( 3.8A)
CHD  A 130 (-3.4A)
 0.00A 2qo4A-2qo4A:
27.7		 2qo4A-2qo4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO5_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 9 LYS A  56
MET A  73
LEU A 111
MET A 118
ARG A 120
 CHD  A 130 (-2.9A)
None
CHD  A 130 ( 4.9A)
CHD  A 130 ( 3.8A)
CHD  A 130 (-3.4A)
 0.94A 2qo5A-2qo4A:
22.3		 2qo5A-2qo4A:
98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO5_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		6 / 9 TYR A  14
ALA A  31
LYS A  56
LEU A 111
MET A 118
ARG A 120
 None
CHD  A 130 ( 3.8A)
CHD  A 130 (-2.9A)
CHD  A 130 ( 4.9A)
CHD  A 130 ( 3.8A)
CHD  A 130 (-3.4A)
 0.67A 2qo5A-2qo4A:
22.3		 2qo5A-2qo4A:
98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO5_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		7 / 9 TYR A  14
LEU A  18
VAL A  27
ALA A  31
LEU A 111
MET A 118
ARG A 120
 None
CHD  A 130 ( 4.7A)
None
CHD  A 130 ( 3.8A)
CHD  A 130 ( 4.9A)
CHD  A 130 ( 3.8A)
CHD  A 130 (-3.4A)
 0.51A 2qo5A-2qo4A:
22.3		 2qo5A-2qo4A:
98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		6 / 12 ILE A  21
ILE A  49
ILE A  70
THR A  72
VAL A  82
LEU A 111
 GOL  A 145 ( 4.8A)
IPA  A 141 (-3.9A)
IPA  A 141 ( 4.5A)
GOL  A 145 (-3.2A)
None
CHD  A 130 ( 4.9A)
 0.81A 2qo5A-2qo4A:
22.3		 2qo5A-2qo4A:
98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		6 / 12 ILE A  21
ILE A  49
THR A  72
VAL A  82
HIS A  98
LEU A 111
 GOL  A 145 ( 4.8A)
IPA  A 141 (-3.9A)
GOL  A 145 (-3.2A)
None
IPA  A 140 (-3.7A)
CHD  A 130 ( 4.9A)
 0.97A 2qo5A-2qo4A:
22.3		 2qo5A-2qo4A:
98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		12 / 12 TYR A  14
LEU A  18
ILE A  21
LEU A  23
ALA A  31
VAL A  34
THR A  72
ASP A  74
PHE A  96
HIS A  98
MET A 118
ARG A 120
 None
CHD  A 130 ( 4.7A)
GOL  A 145 ( 4.8A)
CHD  A 130 ( 4.6A)
CHD  A 130 ( 3.8A)
CHD  A 130 ( 4.8A)
GOL  A 145 (-3.2A)
GOL  A 145 ( 2.8A)
CHD  A 130 ( 4.6A)
IPA  A 140 (-3.7A)
CHD  A 130 ( 3.8A)
CHD  A 130 (-3.4A)
 0.08A 2qo6A-2qo4A:
27.1		 2qo6A-2qo4A:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 ASN A  60
PHE A  62
THR A  72
VAL A  82
LEU A  89
 IPA  A 141 ( 4.7A)
IPA  A 142 ( 4.4A)
GOL  A 145 (-3.2A)
None
IPA  A 142 ( 4.7A)
 0.73A 3elzA-2qo4A:
20.3		 3elzA-2qo4A:
45.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		6 / 12 PHE A  17
ILE A  21
ASN A  60
THR A  72
VAL A  82
LEU A  89
 None
GOL  A 145 ( 4.8A)
IPA  A 141 ( 4.7A)
GOL  A 145 (-3.2A)
None
IPA  A 142 ( 4.7A)
 0.99A 3em0B-2qo4A:
20.2		 3em0B-2qo4A:
45.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 7 LYS A  88
GLU A 101
VAL A 108
THR A 110
 None
 0.40A 3em0B-2qo4A:
20.2		 3em0B-2qo4A:
45.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 5 LYS A  35
PRO A  36
SER A  51
SER A 122
 None
None
IPA  A 141 ( 3.7A)
None
 1.08A 3iluH-2qo4A:
undetectable		 3iluH-2qo4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 5 GLY A  87
LYS A  88
GLU A 101
GLY A  86
 None
 0.70A 3onnA-2qo4A:
undetectable		 3onnA-2qo4A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 5 VAL A  37
ILE A  40
PHE A  47
PHE A  62
 None
None
None
IPA  A 142 ( 4.4A)
 1.05A 3owxB-2qo4A:
undetectable		 3owxB-2qo4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 5 PHE A   2
LEU A  84
GLY A  86
ILE A 102
 None
 0.85A 3wrkA-2qo4A:
undetectable		 3wrkA-2qo4A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		4 / 5 PHE A   2
LEU A  84
GLY A  86
ILE A 102
 None
 0.97A 5ik1A-2qo4A:
undetectable		 5ik1A-2qo4A:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN
(Danio
rerio) 		5 / 12 TYR A  14
ILE A  70
THR A  72
LEU A  89
GLU A 109
 None
IPA  A 141 ( 4.5A)
GOL  A 145 (-3.2A)
IPA  A 142 ( 4.7A)
None
 0.92A 5l8oB-2qo4A:
20.9		 5l8oB-2qo4A:
43.41