SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		4 / 5 GLU A 104
THR A  41
LEU A 110
LEU A 106
 None
 1.08A 1u18B-2qogA:
undetectable		 1u18B-2qogA:
23.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		4 / 6 LEU A   2
ALA A  18
HIS A  48
TYR A  52
 None
 0.80A 2dpzA-2qogA:
20.2		 2dpzA-2qogA:
59.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		4 / 6 LEU A   2
ALA A  23
HIS A  48
TYR A  52
 None
 1.19A 2dpzA-2qogA:
20.2		 2dpzA-2qogA:
59.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
 1.10A 2dpzA-2qogA:
20.2		 2dpzA-2qogA:
59.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.62A 3oshA-2qogA:
17.3		 3oshA-2qogA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		4 / 5 PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.68A 3r0lD-2qogA:
21.2		 3r0lD-2qogA:
96.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 2qog PHOSPHOLIPASE A2 CB2
(Crotalus
durissus) 		5 / 12 ARG A 100
PHE A   5
ALA A 103
ALA A 102
VAL A 101
 None
 1.05A 6c2mC-2qogA:
undetectable		 6c2mC-2qogA:
14.84