SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qoj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 7 ILE Z 132
ILE Z 169
LEU Z 201
ILE Z 178
 None
 0.89A 2q83A-2qojZ:
undetectable		 2q83A-2qojZ:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 12 ILE Z 169
ILE Z 145
PHE Z 167
ILE Z 132
VAL Z 221
 None
 1.02A 2ygoA-2qojZ:
undetectable		 2ygoA-2qojZ:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 12 LEU Z  36
ILE Z  47
LEU Z  51
PHE Z  85
PHE Z  19
 None
 0.99A 2ygpA-2qojZ:
undetectable		 2ygpA-2qojZ:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 8 VAL Z 203
LEU Z 238
TYR Z 244
TYR Z 231
 None
 1.00A 3af0A-2qojZ:
undetectable		 3af0A-2qojZ:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 PHE Z 187
SER Z 205
LEU Z 216
PHE Z 215
ILE Z 145
 None
 1.43A 3ko0A-2qojZ:
undetectable
3ko0B-2qojZ:
undetectable
3ko0C-2qojZ:
undetectable
3ko0D-2qojZ:
undetectable		 3ko0A-2qojZ:
17.93
3ko0B-2qojZ:
17.93
3ko0C-2qojZ:
17.93
3ko0D-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 LEU Z 216
PHE Z 215
ILE Z 145
PHE Z 187
SER Z 205
 None
 1.37A 3ko0C-2qojZ:
undetectable
3ko0D-2qojZ:
undetectable
3ko0E-2qojZ:
undetectable
3ko0F-2qojZ:
undetectable		 3ko0C-2qojZ:
17.93
3ko0D-2qojZ:
17.93
3ko0E-2qojZ:
17.93
3ko0F-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 SER Z 205
PHE Z 187
LEU Z 216
PHE Z 215
ILE Z 145
 None
 1.36A 3ko0C-2qojZ:
undetectable
3ko0D-2qojZ:
undetectable
3ko0E-2qojZ:
undetectable
3ko0F-2qojZ:
undetectable		 3ko0C-2qojZ:
17.93
3ko0D-2qojZ:
17.93
3ko0E-2qojZ:
17.93
3ko0F-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 LEU Z 216
PHE Z 215
ILE Z 145
PHE Z 187
SER Z 205
 None
 1.34A 3ko0E-2qojZ:
undetectable
3ko0F-2qojZ:
undetectable
3ko0G-2qojZ:
undetectable
3ko0H-2qojZ:
undetectable		 3ko0E-2qojZ:
17.93
3ko0F-2qojZ:
17.93
3ko0G-2qojZ:
17.93
3ko0H-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 12 LEU Z 216
PHE Z 215
ILE Z 145
PHE Z 187
SER Z 205
 None
 1.41A 3ko0G-2qojZ:
undetectable
3ko0H-2qojZ:
undetectable
3ko0I-2qojZ:
undetectable
3ko0J-2qojZ:
undetectable		 3ko0G-2qojZ:
17.93
3ko0H-2qojZ:
17.93
3ko0I-2qojZ:
17.93
3ko0J-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 SER Z 205
PHE Z 187
LEU Z 216
PHE Z 215
ILE Z 145
 None
 1.39A 3ko0K-2qojZ:
undetectable
3ko0L-2qojZ:
undetectable
3ko0M-2qojZ:
undetectable
3ko0N-2qojZ:
undetectable		 3ko0K-2qojZ:
17.93
3ko0L-2qojZ:
17.93
3ko0M-2qojZ:
17.93
3ko0N-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 LEU Z 216
PHE Z 215
ILE Z 145
PHE Z 187
SER Z 205
 None
 1.33A 3ko0O-2qojZ:
undetectable
3ko0P-2qojZ:
undetectable
3ko0Q-2qojZ:
undetectable
3ko0R-2qojZ:
undetectable		 3ko0O-2qojZ:
17.93
3ko0P-2qojZ:
17.93
3ko0Q-2qojZ:
17.93
3ko0R-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 11 SER Z 205
PHE Z 187
LEU Z 216
PHE Z 215
ILE Z 145
 None
 1.33A 3ko0Q-2qojZ:
undetectable
3ko0R-2qojZ:
undetectable
3ko0S-2qojZ:
undetectable
3ko0T-2qojZ:
undetectable		 3ko0Q-2qojZ:
17.93
3ko0R-2qojZ:
17.93
3ko0S-2qojZ:
17.93
3ko0T-2qojZ:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 6 LEU Z 141
PHE Z 137
ILE Z 132
ALA Z 180
 None
 1.01A 3mdrA-2qojZ:
undetectable		 3mdrA-2qojZ:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 12 PHE Z  85
GLU Z 148
GLY Z  15
ILE Z  34
GLY Z  11
 None
MG  Z 601 ( 2.4A)
MG  Z 603 ( 3.5A)
None
None
 1.30A 3ps9A-2qojZ:
undetectable		 3ps9A-2qojZ:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 8 ILE Z 131
LEU Z 177
PHE Z 144
GLY Z  15
 None
None
None
MG  Z 603 ( 3.5A)
 1.02A 3selX-2qojZ:
undetectable		 3selX-2qojZ:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 6 ILE Z 131
LEU Z 177
PHE Z 144
GLY Z  15
 None
None
None
MG  Z 603 ( 3.5A)
 1.05A 3sj1X-2qojZ:
undetectable		 3sj1X-2qojZ:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		3 / 3 GLU Z  31
GLY Z  33
SER Z  20
 None
 0.69A 4b53B-2qojZ:
undetectable		 4b53B-2qojZ:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 7 ILE Z 131
LEU Z 177
PHE Z 144
GLY Z  15
 None
None
None
MG  Z 603 ( 3.5A)
 1.05A 4hc3A-2qojZ:
undetectable		 4hc3A-2qojZ:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		5 / 12 GLN Z 230
CYH Z 150
LYS Z 202
ALA Z 165
TYR Z 244
 None
 1.36A 4pclB-2qojZ:
undetectable		 4pclB-2qojZ:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII
(Aspergillus
nidulans) 		4 / 8 LEU Z 177
PHE Z 137
ILE Z 132
LEU Z 201
 None
 0.90A 5eseA-2qojZ:
undetectable		 5eseA-2qojZ:
18.62