SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		3 / 3 ASP A1031
ARG A1273
ILE A1035
 None
 0.87A 1a4gB-2qomA:
undetectable		 1a4gB-2qomA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		4 / 4 HIS A1127
ASP A1088
SER A1090
ASP A1129
 None
 1.21A 1n2xA-2qomA:
undetectable		 1n2xA-2qomA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		3 / 3 SER A1179
ASP A1243
ASP A1058
 None
 0.83A 3uj7A-2qomA:
undetectable		 3uj7A-2qomA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		3 / 3 SER A1179
ASP A1243
ASP A1058
 None
 0.83A 4mwzA-2qomA:
undetectable		 4mwzA-2qomA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		4 / 8 GLY A1246
TYR A1150
SER A1148
HIS A1128
 None
 0.94A 4wryA-2qomA:
undetectable		 4wryA-2qomA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		4 / 8 GLY A1246
TYR A1150
SER A1148
HIS A1128
 None
 0.97A 4wrzA-2qomA:
undetectable		 4wrzA-2qomA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		4 / 8 GLY A1246
TYR A1150
SER A1148
HIS A1128
 None
 0.94A 4ws1A-2qomA:
undetectable		 4ws1A-2qomA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		5 / 12 GLY A1140
ILE A1250
GLY A1246
PHE A1183
THR A1141
 None
 1.26A 5eslA-2qomA:
undetectable		 5eslA-2qomA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		3 / 3 TRP A1166
GLU A1168
ASP A1031
 None
 1.02A 5gqbA-2qomA:
undetectable		 5gqbA-2qomA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		5 / 12 VAL A1084
VAL A1178
ASN A1130
VAL A1103
TYR A1125
 None
 1.48A 6h7lA-2qomA:
undetectable		 6h7lA-2qomA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2qom SERINE PROTEASE ESPP
(Escherichia
coli) 		5 / 12 VAL A1084
VAL A1178
ASN A1130
VAL A1103
TYR A1125
 None
 1.47A 6h7lB-2qomA:
undetectable		 6h7lB-2qomA:
16.08