SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		4 / 5 THR A  12
VAL A  19
LEU A  23
GLN A  26
 None
 0.86A 1fbmE-2qopA:
undetectable		 1fbmE-2qopA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		5 / 11 LEU A  86
LEU A 145
ALA A 164
MET A 167
LEU A 198
 None
 1.19A 1iiuA-2qopA:
undetectable		 1iiuA-2qopA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		3 / 3 CYH A 117
LYS A 116
HIS A 115
 None
 0.89A 5js5A-2qopA:
undetectable		 5js5A-2qopA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		3 / 3 ARG A 192
PHE A  81
ARG A  90
 None
 1.00A 5y9yA-2qopA:
undetectable		 5y9yA-2qopA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		4 / 7 ALA A 163
LEU A 154
CYH A 148
ILE A  92
 None
 0.89A 6b5vA-2qopA:
undetectable
6b5vB-2qopA:
undetectable		 6b5vA-2qopA:
15.81
6b5vB-2qopA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		3 / 3 GLU A  91
ASP A  84
PRO A  82
 None
 0.78A 6berA-2qopA:
undetectable		 6berA-2qopA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR
(Escherichia
coli) 		5 / 9 LEU A  58
ARG A 105
ALA A  20
VAL A  19
ASP A  18
 None
 1.11A 6c2mB-2qopA:
undetectable		 6c2mB-2qopA:
14.42