SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 11 VAL A  15
GLY A  16
LEU A  20
GLY A  11
GLU A 181
POP  A 198 (-3.8A)
POP  A 198 (-3.3A)
None
None
None
0.90A 1iolA-2qorA:
3.3
1iolA-2qorA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 ILE A 131
ASN A 172
GLY A  14
GLY A  16
LEU A 136
None
None
POP  A 198 (-3.3A)
POP  A 198 (-3.3A)
None
1.16A 2zw9A-2qorA:
undetectable
2zw9A-2qorA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
4 / 8 SER A  37
GLY A  11
ASN A 103
ALA A 161
5GP  A 197 (-2.5A)
None
5GP  A 197 (-3.5A)
None
0.95A 3aodA-2qorA:
undetectable
3aodA-2qorA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
4 / 5 LEU A 132
ARG A 139
LEU A 154
PRO A  12
None
POP  A 198 (-2.8A)
None
None
1.17A 3onnA-2qorA:
undetectable
3onnA-2qorA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
4 / 6 TYR A  88
PHE A 100
PRO A   6
LEU A 110
None
1.42A 3tgvD-2qorA:
undetectable
3tgvD-2qorA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
4 / 5 TYR A 121
SER A 113
ASP A 118
ILE A   4
None
1.32A 3uj7B-2qorA:
undetectable
3uj7B-2qorA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 LEU A 186
ILE A  21
VAL A  24
LEU A  25
PHE A  28
None
1.12A 3w67D-2qorA:
undetectable
3w67D-2qorA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 LEU A 186
ILE A  21
VAL A  24
LEU A  25
PHE A  28
None
1.06A 3w68A-2qorA:
undetectable
3w68A-2qorA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 VAL A   8
ILE A  21
VAL A  24
LEU A  25
PHE A  28
None
1.19A 3w68A-2qorA:
undetectable
3w68A-2qorA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 LEU A 186
ILE A  21
VAL A  24
LEU A  25
PHE A  28
None
1.04A 3w68D-2qorA:
undetectable
3w68D-2qorA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
3 / 3 MET A 102
MET A 158
TYR A 121
None
1.19A 4p6xI-2qorA:
undetectable
4p6xI-2qorA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
5 / 12 LEU A 175
VAL A 124
LEU A 186
GLY A  11
PRO A  12
None
1.08A 5ienA-2qorA:
undetectable
5ienA-2qorA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2qor GUANYLATE KINASE
(Plasmodium
vivax)
4 / 5 ARG A 156
MET A 158
THR A 155
LEU A 154
None
1.43A 5z86J-2qorA:
undetectable
5z86J-2qorA:
14.79