SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 1.04A 1fbyA-2qpmA:
undetectable		 1fbyA-2qpmA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 LEU A 254
GLY A 362
LEU A 357
TYR A 256
 None
 0.96A 1jlbA-2qpmA:
5.7		 1jlbA-2qpmA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 5 SER A 436
PHE A 281
VAL A 451
PHE A 452
 None
 1.31A 1oipA-2qpmA:
undetectable		 1oipA-2qpmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 LEU A 254
GLY A 362
LEU A 357
TYR A 256
 None
 0.93A 1s1xA-2qpmA:
2.1		 1s1xA-2qpmA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 7 TYR A 431
GLU A 288
LEU A 458
TYR A 491
 None
None
246  A1536 (-4.3A)
FAD  A1535 ( 4.3A)
 1.05A 1tuvA-2qpmA:
3.8		 1tuvA-2qpmA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 1.04A 1xdkE-2qpmA:
undetectable		 1xdkE-2qpmA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 0.98A 1xiuA-2qpmA:
undetectable		 1xiuA-2qpmA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 107
GLY A 104
ASP A  60
ALA A 111
ALA A  99
 None
FAD  A1535 (-3.3A)
None
FAD  A1535 ( 3.7A)
FAD  A1535 ( 4.3A)
 1.06A 2br4A-2qpmA:
undetectable		 2br4A-2qpmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 107
GLY A 104
ASP A  60
ALA A 111
ALA A  99
 None
FAD  A1535 (-3.3A)
None
FAD  A1535 ( 3.7A)
FAD  A1535 ( 4.3A)
 1.08A 2br4B-2qpmA:
undetectable		 2br4B-2qpmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 107
GLY A 104
ASP A  60
ALA A 111
ALA A  99
 None
FAD  A1535 (-3.3A)
None
FAD  A1535 ( 3.7A)
FAD  A1535 ( 4.3A)
 1.05A 2br4C-2qpmA:
undetectable		 2br4C-2qpmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 107
GLY A 104
ASP A  60
ALA A 111
ALA A  99
 None
FAD  A1535 (-3.3A)
None
FAD  A1535 ( 3.7A)
FAD  A1535 ( 4.3A)
 1.07A 2br4E-2qpmA:
undetectable		 2br4E-2qpmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 107
GLY A 104
ASP A  60
ALA A 111
ALA A  99
 None
FAD  A1535 (-3.3A)
None
FAD  A1535 ( 3.7A)
FAD  A1535 ( 4.3A)
 1.15A 2br4F-2qpmA:
undetectable		 2br4F-2qpmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A 357
GLY A 282
PHE A 281
VAL A 287
ALA A 332
 None
 1.35A 2kceA-2qpmA:
undetectable		 2kceA-2qpmA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 ILE A 195
GLY A 227
LEU A 229
PHE A 401
 None
 0.78A 2vctA-2qpmA:
undetectable		 2vctA-2qpmA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 ILE A 195
GLY A 227
LEU A 229
PHE A 401
 None
 0.79A 2vctB-2qpmA:
undetectable		 2vctB-2qpmA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVO_A_PAUA314_0
(PANTOTHENATE KINASE)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 11 LEU A 229
HIS A 504
TYR A 491
PHE A 401
ILE A 195
 None
None
FAD  A1535 ( 4.3A)
None
None
 1.31A 3avoA-2qpmA:
0.0		 3avoA-2qpmA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 PHE A 292
ALA A 302
THR A 304
VAL A 255
 None
 0.85A 3me6B-2qpmA:
undetectable		 3me6B-2qpmA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 0.97A 3oapA-2qpmA:
undetectable		 3oapA-2qpmA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 5 VAL A 291
PHE A 307
ILE A 315
PHE A 365
 None
 1.01A 3owxB-2qpmA:
undetectable		 3owxB-2qpmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 LEU A 375
GLN A 187
TYR A 371
PHE A 374
 None
 1.11A 3po7A-2qpmA:
undetectable		 3po7A-2qpmA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 11 VAL A 118
ALA A 113
GLY A 116
TYR A  96
LYS A 517
 None
 1.50A 3qxyB-2qpmA:
undetectable
3qxyQ-2qpmA:
undetectable		 3qxyB-2qpmA:
23.61
3qxyQ-2qpmA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 5 ILE A 184
PRO A 193
SER A 180
GLY A 183
 FAD  A1535 (-4.2A)
None
FAD  A1535 (-3.2A)
FAD  A1535 (-3.3A)
 1.13A 3tkdB-2qpmA:
undetectable		 3tkdB-2qpmA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 5 ILE A 184
PRO A 193
SER A 180
GLY A 183
 FAD  A1535 (-4.2A)
None
FAD  A1535 (-3.2A)
FAD  A1535 (-3.3A)
 1.15A 3tkdA-2qpmA:
undetectable		 3tkdA-2qpmA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 7 GLY A 192
PHE A 401
PHE A 452
LEU A 433
 None
 0.89A 3v7pA-2qpmA:
undetectable		 3v7pA-2qpmA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		3 / 3 ARG A 377
ARG A 253
TRP A 251
 None
 1.32A 4cpzC-2qpmA:
undetectable		 4cpzC-2qpmA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 8 GLY A  62
ASN A  63
ARG A 392
PHE A 112
 None
NAG  A1601 (-1.8A)
None
None
 0.95A 4j4vC-2qpmA:
undetectable		 4j4vC-2qpmA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 11 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 0.98A 4nqaA-2qpmA:
undetectable		 4nqaA-2qpmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 VAL A 414
PHE A 459
LEU A 470
ARG A 469
ARG A 476
 None
 1.35A 4po0A-2qpmA:
2.3		 4po0A-2qpmA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		4 / 7 SER A 185
PHE A 374
GLU A 331
GLU A 288
 None
 1.13A 4xzkA-2qpmA:
undetectable		 4xzkA-2qpmA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 GLY A 230
GLY A 228
ILE A 532
ILE A 235
PHE A 100
 FAD  A1535 (-3.4A)
None
None
FAD  A1535 (-3.8A)
None
 1.11A 5fa8A-2qpmA:
undetectable		 5fa8A-2qpmA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		3 / 3 THR A 308
ASP A 309
ALA A 310
 None
 0.09A 5g5gB-2qpmA:
5.6		 5g5gB-2qpmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 11 ASP A  80
LEU A  47
VAL A 117
ILE A  98
ILE A 204
 None
 1.17A 5gpgA-2qpmA:
undetectable		 5gpgA-2qpmA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 SER A 456
ASN A 399
GLU A 288
GLU A 331
GLU A 381
 246  A1536 (-3.3A)
246  A1536 (-3.4A)
None
None
246  A1536 (-3.3A)
 1.42A 5iqdC-2qpmA:
0.0		 5iqdC-2qpmA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 SER A 456
ASN A 399
GLU A 288
GLU A 331
GLU A 381
 246  A1536 (-3.3A)
246  A1536 (-3.4A)
None
None
246  A1536 (-3.3A)
 1.33A 5iqeD-2qpmA:
0.0		 5iqeD-2qpmA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 0.97A 5z12B-2qpmA:
undetectable		 5z12B-2qpmA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 ILE A 315
ALA A 313
LEU A 301
ALA A 302
VAL A 360
 None
 1.00A 5z12C-2qpmA:
undetectable		 5z12C-2qpmA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 12 LEU A  47
ASP A  80
LEU A  84
ALA A  87
SER A  90
 None
 1.05A 6b0iB-2qpmA:
undetectable		 6b0iB-2qpmA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 10 SER A 456
ASN A 399
GLU A 288
GLU A 331
GLU A 381
 246  A1536 (-3.3A)
246  A1536 (-3.4A)
None
None
246  A1536 (-3.3A)
 1.44A 6cggB-2qpmA:
0.0		 6cggB-2qpmA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 2qpm CYTOKININ
DEHYDROGENASE 1
(Zea
mays) 		5 / 11 SER A 456
ASN A 399
GLU A 288
GLU A 331
GLU A 381
 246  A1536 (-3.3A)
246  A1536 (-3.4A)
None
None
246  A1536 (-3.3A)
 1.35A 6cggD-2qpmA:
0.3		 6cggD-2qpmA:
17.33