SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 7 TYR A 310
HIS A 326
THR A 250
ASN A 289
 None
 1.38A 1afsA-2qpsA:
5.8		 1afsA-2qpsA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 7 TYR A 310
HIS A 326
THR A 250
ASN A 289
 None
 1.38A 1afsB-2qpsA:
3.7		 1afsB-2qpsA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 ALA A 388
VAL A 391
TRP A 402
 None
 0.99A 1c4dA-2qpsA:
undetectable
1c4dB-2qpsA:
undetectable		 1c4dA-2qpsA:
4.68
1c4dB-2qpsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 THR A 285
THR A  36
HIS A   1
LEU A 314
 None
 1.36A 1d4fC-2qpsA:
undetectable		 1d4fC-2qpsA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		6 / 12 TYR A  52
ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.70A 1dedB-2qpsA:
28.1		 1dedB-2qpsA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 PHE A   8
TYR A  52
PRO A  41
 None
 1.10A 1mcnA-2qpsA:
undetectable
1mcnB-2qpsA:
undetectable
1mcnP-2qpsA:
undetectable		 1mcnA-2qpsA:
19.48
1mcnB-2qpsA:
19.48
1mcnP-2qpsA:
0.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		9 / 12 TRP A  10
TYR A  52
HIS A  93
ARG A 178
ASP A 180
GLU A 205
TRP A 207
HIS A 290
ASP A 291
 None
 0.39A 1mxdA-2qpsA:
40.6		 1mxdA-2qpsA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		9 / 12 TRP A  10
TYR A  52
HIS A  93
PHE A 144
ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.66A 1mxdA-2qpsA:
40.6		 1mxdA-2qpsA:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 GLY A   7
GLN A   6
TRP A  39
SER A  12
 None
 1.26A 1p6kB-2qpsA:
undetectable		 1p6kB-2qpsA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 7 ASP A 149
ASP A 143
ASP A 139
HIS A 152
 CA  A 502 ( 3.3A)
CA  A 502 (-2.8A)
CA  A 500 (-2.3A)
None
 1.49A 1t03A-2qpsA:
undetectable		 1t03A-2qpsA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 PHE A 174
TYR A  20
TYR A  65
 None
 0.95A 1x70B-2qpsA:
undetectable		 1x70B-2qpsA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 GLY A   7
GLN A   6
TRP A  39
SER A  12
 None
 1.15A 1zzuA-2qpsA:
0.3		 1zzuA-2qpsA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 LEU A 354
PRO A 273
ALA A 272
ILE A 356
 None
 0.99A 2aofB-2qpsA:
undetectable		 2aofB-2qpsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 10 TYR A 185
LEU A 117
LEU A 161
HIS A 152
LEU A 165
 None
 1.13A 2bxeB-2qpsA:
undetectable		 2bxeB-2qpsA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 11 ILE A  75
LEU A  78
ALA A  31
ILE A 322
VAL A  83
 None
 0.89A 2fxdA-2qpsA:
undetectable		 2fxdA-2qpsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 11 TYR A  52
ASP A 180
HIS A 290
ASP A 291
TRP A  10
 None
 0.85A 2owcA-2qpsA:
14.1		 2owcA-2qpsA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 11 TYR A  52
ASP A 180
HIS A 290
ASP A 291
TRP A  10
 None
 0.87A 2owwA-2qpsA:
14.0		 2owwA-2qpsA:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QPU_B_QPSB3000_1
(ALPHA-AMYLASE TYPE A
ISOZYME)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		8 / 9 LYS A 375
ASP A 381
VAL A 382
THR A 392
HIS A 395
ASP A 398
ALA A 400
TRP A 402
 None
 0.73A 2qpuB-2qpsA:
69.9		 2qpuB-2qpsA:
99.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 MET A 298
GLU A 205
ASN A  92
 None
None
CA  A 500 (-2.9A)
 1.06A 3a27A-2qpsA:
undetectable		 3a27A-2qpsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.67A 3aicA-2qpsA:
9.4		 3aicA-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.65A 3aicB-2qpsA:
7.1		 3aicB-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		6 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
TYR A  52
 None
 0.66A 3aicC-2qpsA:
9.5		 3aicC-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.74A 3aicD-2qpsA:
9.5		 3aicD-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.68A 3aicE-2qpsA:
9.5		 3aicE-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.67A 3aicF-2qpsA:
9.4		 3aicF-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.65A 3aicG-2qpsA:
9.5		 3aicG-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.72A 3aicH-2qpsA:
9.5		 3aicH-2qpsA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 9 LEU A 354
VAL A 372
ILE A 342
ILE A 313
ILE A 368
 None
 1.11A 3ekqB-2qpsA:
undetectable		 3ekqB-2qpsA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 9 LEU A 354
VAL A 372
ILE A 342
ALA A 366
ILE A 368
 None
 0.78A 3el0B-2qpsA:
undetectable		 3el0B-2qpsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 9 VAL A 372
ILE A 342
ILE A 313
ALA A 366
ILE A 368
 None
 0.96A 3el0B-2qpsA:
undetectable		 3el0B-2qpsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 LEU A  74
GLY A 173
LEU A  40
PRO A  43
TYR A  20
 None
 1.13A 3mecA-2qpsA:
undetectable		 3mecA-2qpsA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 GLY A 396
GLY A 309
VAL A 374
ASP A 288
PHE A 301
 None
 1.33A 3qowA-2qpsA:
undetectable		 3qowA-2qpsA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 ASP A 325
SER A 294
GLY A 293
TRP A 330
 None
 1.49A 3w9tB-2qpsA:
undetectable		 3w9tB-2qpsA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 ASP A 325
SER A 294
GLY A 293
TRP A 330
 None
 1.50A 3w9tC-2qpsA:
undetectable		 3w9tC-2qpsA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF501_1
(HEMOLYTIC LECTIN
CEL-III)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 4 ASP A 325
SER A 294
GLY A 293
TRP A 330
 None
 1.50A 3w9tF-2qpsA:
0.0		 3w9tF-2qpsA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 LEU A 254
LYS A 251
THR A 250
 None
 0.60A 4lj0A-2qpsA:
undetectable		 4lj0A-2qpsA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 11 TYR A 193
HIS A  93
HIS A 152
LEU A 161
LEU A 165
 None
 1.33A 4m7tA-2qpsA:
2.3		 4m7tA-2qpsA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 PRO A 320
ILE A 313
VAL A 306
ASP A 325
ILE A 336
 None
 1.35A 4xe0A-2qpsA:
undetectable		 4xe0A-2qpsA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ARG A 178
ASP A 180
GLU A 205
HIS A 290
ASP A 291
 None
 0.52A 5csyB-2qpsA:
5.1		 5csyB-2qpsA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 LEU A 201
LEU A  71
PHE A 174
ILE A  75
HIS A  79
 None
 1.24A 5dv4A-2qpsA:
undetectable		 5dv4A-2qpsA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 1.03A 5n0sA-2qpsA:
undetectable		 5n0sA-2qpsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 1.04A 5n0sB-2qpsA:
undetectable		 5n0sB-2qpsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 1.00A 5n0tA-2qpsA:
undetectable		 5n0tA-2qpsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 0.99A 5n0tB-2qpsA:
undetectable		 5n0tB-2qpsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 0.95A 5n0wB-2qpsA:
undetectable		 5n0wB-2qpsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 0.99A 5n0xA-2qpsA:
undetectable		 5n0xA-2qpsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ILE A 368
VAL A 385
PHE A 390
ILE A 342
VAL A 401
 None
 0.96A 5n4iA-2qpsA:
undetectable		 5n4iA-2qpsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		5 / 12 ASP A 208
PHE A 246
ILE A  86
ILE A 194
ALA A 190
 None
 1.20A 5vc0A-2qpsA:
undetectable		 5vc0A-2qpsA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		6 / 12 TRP A  10
TYR A  52
HIS A  93
ASP A 180
HIS A 290
ASP A 291
 None
 0.50A 6ag0A-2qpsA:
36.2		 6ag0A-2qpsA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		3 / 3 TYR A  20
ALA A  77
LEU A  78
 None
 0.64A 6ag0C-2qpsA:
36.3		 6ag0C-2qpsA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 THR A 285
THR A  36
HIS A   1
LEU A 314
 None
 1.33A 6aphA-2qpsA:
undetectable		 6aphA-2qpsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 5 THR A 285
THR A  36
HIS A   1
LEU A 314
 None
 1.33A 6gbnB-2qpsA:
undetectable		 6gbnB-2qpsA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 2qps ALPHA-AMYLASE TYPE A
ISOZYME
(Hordeum
vulgare) 		4 / 8 GLY A 377
GLY A 361
LEU A 262
GLU A 259
 None
 0.70A 6mdqA-2qpsA:
undetectable		 6mdqA-2qpsA:
11.02