SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 11 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.95A 1c6yA-2qpzA:
undetectable		 1c6yA-2qpzA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 10 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.89A 1hsgA-2qpzA:
undetectable		 1hsgA-2qpzA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.84A 2avsA-2qpzA:
undetectable		 2avsA-2qpzA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.95A 2pymB-2qpzA:
undetectable		 2pymB-2qpzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.93A 2pynB-2qpzA:
undetectable		 2pynB-2qpzA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 6 ASP A 101
ILE A 100
LEU A  28
GLU A  24
 None
 0.97A 2ya7A-2qpzA:
undetectable		 2ya7A-2qpzA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 6 ASP A 101
ILE A 100
LEU A  28
GLU A  24
 None
 0.97A 2ya7B-2qpzA:
undetectable		 2ya7B-2qpzA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 6 ASP A 101
ILE A 100
LEU A  28
GLU A  24
 None
 0.96A 2ya7D-2qpzA:
undetectable		 2ya7D-2qpzA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 10 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.99A 3em3B-2qpzA:
undetectable		 3em3B-2qpzA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.85A 3k4vB-2qpzA:
undetectable		 3k4vB-2qpzA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 10 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.95A 3oxwB-2qpzA:
undetectable		 3oxwB-2qpzA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.87A 3pwrB-2qpzA:
undetectable		 3pwrB-2qpzA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.87A 3tl9B-2qpzA:
undetectable		 3tl9B-2qpzA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 11 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.85A 4njtC-2qpzA:
undetectable		 4njtC-2qpzA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 11 LEU A 102
ALA A   7
VAL A  91
ILE A  37
ILE A 100
 None
 0.94A 4qgiB-2qpzA:
undetectable		 4qgiB-2qpzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		3 / 3 LYS A   1
TRP A   4
SER A 103
 None
 0.92A 5nwwA-2qpzA:
undetectable		 5nwwA-2qpzA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 5 THR A  40
CYH A  73
THR A  74
GLY A  75
 None
 1.24A 6gtqA-2qpzA:
undetectable		 6gtqA-2qpzA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		3 / 3 ASP A  17
LEU A  19
ARG A  50
 None
 0.83A 7dfrA-2qpzA:
undetectable		 7dfrA-2qpzA:
20.27