SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		4 / 7 VAL A 235
HIS A 222
THR A 240
LEU A 243
 None
 0.77A 3arrA-2qq2A:
undetectable		 3arrA-2qq2A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		4 / 7 PHE A 320
SER A 283
VAL A 300
VAL A 247
 None
 1.15A 3n61A-2qq2A:
undetectable
3n61B-2qq2A:
undetectable		 3n61A-2qq2A:
17.51
3n61B-2qq2A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		4 / 8 PHE A 320
SER A 283
VAL A 300
VAL A 247
 None
 1.15A 3nlrA-2qq2A:
undetectable
3nlrB-2qq2A:
undetectable		 3nlrA-2qq2A:
17.51
3nlrB-2qq2A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		5 / 10 GLY A 284
ALA A 318
VAL A 298
GLU A 297
VAL A 247
 None
 1.17A 4da7A-2qq2A:
undetectable		 4da7A-2qq2A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		5 / 12 ALA A 315
ASP A 301
ILE A 280
ILE A 282
ILE A 274
 None
 0.90A 4q1xB-2qq2A:
undetectable		 4q1xB-2qq2A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2qq2 CYTOSOLIC ACYL
COENZYME A THIOESTER
HYDROLASE
(Homo
sapiens) 		4 / 7 VAL A 265
ILE A 268
VAL A 298
ALA A 318
 None
 0.74A 5ospA-2qq2A:
undetectable		 5ospA-2qq2A:
18.64