SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		4 / 8 PRO A 956
THR A 926
PRO A 982
SER A 980
 None
 0.96A 2v32C-2qqrA:
undetectable
2v32D-2qqrA:
undetectable		 2v32C-2qqrA:
17.95
2v32D-2qqrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		4 / 8 PRO A 956
THR A 926
PRO A 982
SER A 980
 None
 0.99A 2v41C-2qqrA:
undetectable
2v41D-2qqrA:
undetectable		 2v41C-2qqrA:
17.95
2v41D-2qqrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		4 / 8 PRO A 956
THR A 926
PRO A 982
SER A 980
 None
 0.94A 2v41G-2qqrA:
undetectable
2v41H-2qqrA:
undetectable		 2v41G-2qqrA:
17.95
2v41H-2qqrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 GLN A 916
GLU A 918
LYS A 904
 None
 1.06A 3su9A-2qqrA:
undetectable		 3su9A-2qqrA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		4 / 4 PHE A 977
VAL A 930
ALA A 979
PHE A 937
 None
 1.47A 4f3tA-2qqrA:
3.7		 4f3tA-2qqrA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 TYR A1004
ARG A1000
HIS A 895
 None
 1.25A 4fubA-2qqrA:
undetectable		 4fubA-2qqrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 VAL A 978
GLY A 960
LYS A 976
 None
 0.73A 4k50A-2qqrA:
undetectable		 4k50A-2qqrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 VAL A 978
GLY A 960
LYS A 976
 None
 0.70A 4k50E-2qqrA:
undetectable		 4k50E-2qqrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 GLY A 955
PRO A 956
GLN A 949
 None
 0.46A 4oltB-2qqrA:
undetectable		 4oltB-2qqrA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		3 / 3 GLY A 955
PRO A 956
GLN A 949
 None
 0.58A 4qwpB-2qqrA:
undetectable		 4qwpB-2qqrA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2qqr JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A
(Homo
sapiens) 		4 / 4 PHE A 977
VAL A 930
ALA A 979
PHE A 937
 None
 1.47A 4w5qA-2qqrA:
3.6		 4w5qA-2qqrA:
9.79