SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		5 / 11 ASP A  51
GLU A  52
HIS A 130
GLU A  19
GLU A 127
 None
 1.40A 1rnrA-2qqyA:
9.7		 1rnrA-2qqyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		5 / 11 ASP A 126
GLU A 127
HIS A  55
GLU A  94
GLU A  52
 None
 1.28A 1rnrA-2qqyA:
9.7		 1rnrA-2qqyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		5 / 11 ASP A 126
GLU A 127
HIS A  55
SER A  47
GLU A  52
 None
 1.24A 1rnrA-2qqyA:
9.7		 1rnrA-2qqyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		5 / 12 ASP A 126
GLU A 127
HIS A  55
GLU A  94
GLU A  52
 None
 1.37A 1rnrB-2qqyA:
9.6		 1rnrB-2qqyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		4 / 8 ARG A 136
ASP A 126
GLU A  19
GLU A  94
 None
 1.17A 3dh0A-2qqyA:
undetectable		 3dh0A-2qqyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		4 / 6 ASP A  51
TYR A  26
GLU A  94
GLU A 132
 None
 1.30A 6mn5A-2qqyA:
undetectable		 6mn5A-2qqyA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2qqy SIGMA B OPERON
(Bacillus
anthracis) 		4 / 6 ASP A  51
TYR A  26
GLU A  94
GLU A 132
 None
 1.22A 6mn5C-2qqyA:
undetectable		 6mn5C-2qqyA:
17.69