SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_E_SVRE510_3 (PHOSPHOLIPASE A2)	2qr3	TWO-COMPONENT SYSTEM RESPONSE REGULATOR (Bacteroides fragilis)	4 / 5	VAL A 48 VAL A 49 THR A 117 THR A 3	None	1.20A	3bjwG-2qr3A: undetectable	3bjwG-2qr3A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF509_1 (PHOSPHOLIPASE A2)	2qr3	TWO-COMPONENT SYSTEM RESPONSE REGULATOR (Bacteroides fragilis)	4 / 5	VAL A 48 VAL A 49 THR A 117 THR A 3	None	1.18A	3bjwC-2qr3A: undetectable	3bjwC-2qr3A: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A9K_A_TYLA2200_1 (CREB-BINDING PROTEIN)	2qr3	TWO-COMPONENT SYSTEM RESPONSE REGULATOR (Bacteroides fragilis)	4 / 6	VAL A 17 LEU A 21 ILE A 4 VAL A 105	None	0.88A	4a9kA-2qr3A: undetectable	4a9kA-2qr3A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3Q_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2qr3	TWO-COMPONENT SYSTEM RESPONSE REGULATOR (Bacteroides fragilis)	5 / 12	ILE A 6 ILE A 72 LEU A 37 PRO A 34 ILE A 5	None	1.04A	4p3qA-2qr3A: undetectable	4p3qA-2qr3A: 19.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_E_SVRE510_3","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2qr3","TWO-COMPONENT SYSTEM RESPONSE REGULATOR","Bacteroides fragilis",4,"VAL A  48;VAL A  49;THR A 117;THR A   3","None","1.20A","3bjwG-2qr3A:undetectable","3bjwG-2qr3A:19.23"],["3BJW_F_SVRF509_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2qr3","TWO-COMPONENT SYSTEM RESPONSE REGULATOR","Bacteroides fragilis",4,"VAL A  48;VAL A  49;THR A 117;THR A   3","None","1.18A","3bjwC-2qr3A:undetectable","3bjwC-2qr3A:19.23"],["4A9K_A_TYLA2200_1","CREB-BINDING PROTEIN","2qr3","TWO-COMPONENT SYSTEM RESPONSE REGULATOR","Bacteroides fragilis",4,"VAL A  17;LEU A  21;ILE A   4;VAL A 105","None","0.88A","4a9kA-2qr3A:undetectable","4a9kA-2qr3A:18.38"],["4P3Q_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","2qr3","TWO-COMPONENT SYSTEM RESPONSE REGULATOR","Bacteroides fragilis",5,"ILE A   6;ILE A  72;LEU A  37;PRO A  34;ILE A   5","None","1.04A","4p3qA-2qr3A:undetectable","4p3qA-2qr3A:19.02"]]