SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		3 / 3 VAL A 606
VAL A 656
TRP A 602
 None
 0.89A 1av2C-2qr7A:
undetectable
1av2D-2qr7A:
undetectable		 1av2C-2qr7A:
4.68
1av2D-2qr7A:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 8 LEU A 502
VAL A 606
GLY A 605
TRP A 602
 None
 1.00A 1hrkA-2qr7A:
undetectable		 1hrkA-2qr7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 8 LEU A 502
VAL A 606
GLY A 605
TRP A 602
 None
 0.99A 1hrkB-2qr7A:
undetectable		 1hrkB-2qr7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
THR A 493
LEU A 495
MET A 496
ASP A 561
 None
 0.64A 1m17A-2qr7A:
21.3		 1m17A-2qr7A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ALA A 449
GLU A 463
LEU A 467
THR A 493
LEU A 530
HIS A 537
 None
 0.66A 1uwhA-2qr7A:
20.4		 1uwhA-2qr7A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
THR A 493
LEU A 530
HIS A 537
 None
 0.63A 1uwhB-2qr7A:
20.4		 1uwhB-2qr7A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ILE A 428
ALA A 449
GLU A 463
THR A 493
LEU A 530
HIS A 537
 None
 0.82A 1uwjB-2qr7A:
20.3		 1uwjB-2qr7A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		3 / 3 VAL A 606
VAL A 656
TRP A 602
 None
 0.85A 1w5uC-2qr7A:
undetectable
1w5uD-2qr7A:
undetectable		 1w5uC-2qr7A:
4.68
1w5uD-2qr7A:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 GLY A 594
ALA A 597
ASP A 596
GLY A 534
ALA A 671
 None
 1.06A 2b7zA-2qr7A:
undetectable		 2b7zA-2qr7A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 TYR A 615
THR A 613
TYR A 609
ASN A 691
 None
 0.91A 2g70A-2qr7A:
undetectable		 2g70A-2qr7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 TYR A 615
THR A 613
TYR A 609
ASN A 691
 None
 0.89A 2g70B-2qr7A:
undetectable		 2g70B-2qr7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		3 / 3 VAL A 656
TRP A 602
VAL A 606
 None
 0.89A 2izqA-2qr7A:
undetectable
2izqB-2qr7A:
undetectable		 2izqA-2qr7A:
4.68
2izqB-2qr7A:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 GLY A 594
ALA A 597
ASP A 596
ASP A 600
GLY A 534
ALA A 671
 None
 1.11A 2nmzA-2qr7A:
undetectable		 2nmzA-2qr7A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 6 LEU A 530
ILE A 559
ILE A 505
LEU A 608
 None
 0.81A 2xkwB-2qr7A:
undetectable		 2xkwB-2qr7A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 8 GLU A 513
SER A 649
VAL A 673
HIS A 676
 None
 1.26A 3b9lA-2qr7A:
undetectable		 3b9lA-2qr7A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 VAL A 527
THR A 526
ILE A 523
ILE A 545
 None
 0.84A 3deuA-2qr7A:
undetectable		 3deuA-2qr7A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 11 GLY A 594
ALA A 597
ASP A 596
ASP A 600
VAL A 527
GLY A 534
 None
 1.48A 3ekxA-2qr7A:
undetectable		 3ekxA-2qr7A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 GLY A 594
ALA A 597
ASP A 596
ASP A 600
VAL A 527
GLY A 534
 None
 1.46A 3el5B-2qr7A:
undetectable		 3el5B-2qr7A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 ALA A 449
GLU A 463
LEU A 467
ILE A 477
THR A 493
 None
 0.92A 3gcsA-2qr7A:
18.9		 3gcsA-2qr7A:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 ALA A 449
LEU A 467
ILE A 477
THR A 493
HIS A 537
 None
 0.94A 3gcsA-2qr7A:
18.9		 3gcsA-2qr7A:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ALA A 449
GLU A 463
LEU A 467
ILE A 477
THR A 493
HIS A 537
 None
 0.57A 3gp0A-2qr7A:
19.1		 3gp0A-2qr7A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 GLU A 463
LEU A 467
ILE A 477
THR A 493
HIS A 537
ASP A 561
 None
 1.25A 3gp0A-2qr7A:
19.1		 3gp0A-2qr7A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
ILE A 477
THR A 493
LEU A 495
 None
 0.62A 3hecA-2qr7A:
19.2		 3hecA-2qr7A:
29.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
ILE A 477
THR A 493
 None
 0.90A 3hegA-2qr7A:
2.5		 3hegA-2qr7A:
29.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
THR A 493
MET A 496
 None
 1.30A 3hegA-2qr7A:
2.5		 3hegA-2qr7A:
29.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		3 / 3 VAL A 606
VAL A 656
TRP A 602
 None
 0.85A 3l8lC-2qr7A:
undetectable
3l8lD-2qr7A:
undetectable		 3l8lC-2qr7A:
4.68
3l8lD-2qr7A:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 8 ALA A 449
LYS A 451
GLU A 463
THR A 493
LEU A 495
MET A 496
 None
 0.84A 3lfaA-2qr7A:
19.2		 3lfaA-2qr7A:
29.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 GLY A 429
ALA A 449
LYS A 451
LEU A 467
ILE A 477
THR A 493
 None
 0.60A 3ohtA-2qr7A:
5.4		 3ohtA-2qr7A:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_1
(P38A)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 GLY A 429
ALA A 449
LYS A 451
LEU A 467
ILE A 477
THR A 493
 None
 0.58A 3ohtB-2qr7A:
5.4		 3ohtB-2qr7A:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 8 ILE A 545
VAL A 606
GLY A 605
TRP A 602
 None
 0.80A 3w1wA-2qr7A:
undetectable		 3w1wA-2qr7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
ILE A 477
THR A 493
LEU A 530
HIS A 537
 None
 0.71A 3zosB-2qr7A:
19.0		 3zosB-2qr7A:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
ILE A 476
THR A 493
HIS A 537
 None
 0.59A 4c8bB-2qr7A:
20.3		 4c8bB-2qr7A:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 PHE A 562
ALA A 565
THR A 522
THR A 526
LEU A 540
 None
 1.28A 4qynA-2qr7A:
undetectable		 4qynA-2qr7A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 PHE A 562
ALA A 565
THR A 522
THR A 526
LEU A 540
 None
 1.35A 4qzuA-2qr7A:
undetectable		 4qzuA-2qr7A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 10 ILE A 428
ALA A 449
LYS A 451
ILE A 477
THR A 493
LEU A 495
LEU A 546
 None
 0.59A 4rz7A-2qr7A:
6.1		 4rz7A-2qr7A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 ALA A 449
LYS A 451
THR A 493
ASP A 561
PHE A 562
 None
 0.71A 4xv2A-2qr7A:
20.1		 4xv2A-2qr7A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		6 / 12 ALA A 449
LYS A 451
LEU A 467
THR A 493
ASP A 561
PHE A 562
 None
 0.79A 4xv2B-2qr7A:
20.0		 4xv2B-2qr7A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 ALA A 449
LYS A 451
LEU A 467
THR A 493
PHE A 562
 None
 0.80A 5cswA-2qr7A:
20.1		 5cswA-2qr7A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 12 ALA A 449
LYS A 451
LEU A 467
THR A 493
PHE A 562
 None
 0.81A 5cswB-2qr7A:
20.0		 5cswB-2qr7A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		7 / 12 ALA A 449
LYS A 451
GLU A 463
LEU A 467
THR A 493
LEU A 530
HIS A 537
 None
 0.70A 5hi2A-2qr7A:
20.9		 5hi2A-2qr7A:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 ILE A 428
GLY A 429
ASP A 561
PHE A 562
 None
 0.85A 5hieB-2qr7A:
19.7		 5hieB-2qr7A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 8 ILE A 428
GLY A 429
ASP A 561
PHE A 562
 None
 0.83A 5hieD-2qr7A:
19.8		 5hieD-2qr7A:
24.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 GLY A 429
GLY A 431
SER A 432
LYS A 451
 None
 0.72A 5izfA-2qr7A:
22.7		 5izfA-2qr7A:
31.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		4 / 7 GLY A 429
GLY A 431
LYS A 451
ASP A 561
 None
 0.28A 5j5xA-2qr7A:
22.8		 5j5xA-2qr7A:
31.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 9 ILE A 428
GLY A 429
ALA A 449
ILE A 477
MET A 496
 None
 0.62A 5lw1B-2qr7A:
19.2		 5lw1B-2qr7A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3
(Mus
musculus) 		5 / 10 GLY A 429
ALA A 449
ILE A 477
LEU A 495
MET A 496
 None
 0.64A 5lw1E-2qr7A:
18.9		 5lw1E-2qr7A:
13.45