SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qrd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
(Schizosaccharomy
ces
pombe) 		5 / 12 ILE A 497
SER A 499
TRP A 501
LEU A 573
LEU A 569
 None
 0.94A 1s19A-2qrdA:
undetectable		 1s19A-2qrdA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 2qrd SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B 241
SER B 252
LEU B 254
VAL B 253
ASP B 250
 None
 1.13A 2c12C-2qrdB:
undetectable		 2c12C-2qrdB:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 ASP A 493
THR A 496
TYR A 495
HIS B 235
 None
 1.50A 2dysN-2qrdA:
undetectable
2dysP-2qrdA:
undetectable		 2dysN-2qrdA:
13.89
2dysP-2qrdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 ASP A 493
THR A 496
TYR A 495
HIS B 264
 None
 1.45A 2dysN-2qrdA:
undetectable
2dysP-2qrdA:
undetectable		 2dysN-2qrdA:
13.89
2dysP-2qrdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 ASP A 493
THR A 496
TYR A 495
HIS B 235
 None
 1.48A 2eimA-2qrdA:
undetectable
2eimC-2qrdA:
undetectable		 2eimA-2qrdA:
13.89
2eimC-2qrdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 ASP A 493
THR A 496
TYR A 495
HIS B 235
 None
 1.48A 2einA-2qrdA:
undetectable
2einC-2qrdA:
undetectable		 2einA-2qrdA:
13.89
2einC-2qrdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 6 ASP A 493
THR A 496
TYR A 495
HIS B 264
 None
 1.46A 2einA-2qrdA:
undetectable
2einC-2qrdA:
undetectable		 2einA-2qrdA:
13.89
2einC-2qrdA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2qrd SNF1-LIKE PROTEIN
KINASE SSP2
SPCC1919.03C PROTEIN
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		4 / 4 CYH A 566
LEU B 265
LEU B 277
ALA B 267
 None
 0.99A 5hpuA-2qrdA:
undetectable
5hpuB-2qrdA:
undetectable		 5hpuA-2qrdA:
12.20
5hpuB-2qrdA:
18.92