SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qrx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 2qrx GM27569P
(Drosophila
melanogaster) 		5 / 12 GLN A  84
ALA A  82
VAL A  80
ASP A  90
HIS A  91
 None
 1.25A 1kxhA-2qrxA:
undetectable		 1kxhA-2qrxA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 2qrx GM27569P
(Drosophila
melanogaster) 		4 / 8 ARG A  98
GLN A 147
HIS A  49
GLN A  46
 None
 1.47A 2vxaA-2qrxA:
undetectable
2vxaB-2qrxA:
undetectable
2vxaK-2qrxA:
undetectable		 2vxaA-2qrxA:
14.29
2vxaB-2qrxA:
14.29
2vxaK-2qrxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 2qrx GM27569P
(Drosophila
melanogaster) 		4 / 8 ARG A  98
GLN A 147
HIS A  49
GLN A  46
 None
 1.46A 2vxaB-2qrxA:
undetectable
2vxaC-2qrxA:
undetectable
2vxaG-2qrxA:
undetectable		 2vxaB-2qrxA:
14.29
2vxaC-2qrxA:
14.29
2vxaG-2qrxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 2qrx GM27569P
(Drosophila
melanogaster) 		4 / 8 ARG A  98
GLN A 147
HIS A  49
GLN A  46
 None
 1.46A 2vxaD-2qrxA:
undetectable
2vxaF-2qrxA:
undetectable
2vxaI-2qrxA:
undetectable		 2vxaD-2qrxA:
14.29
2vxaF-2qrxA:
14.29
2vxaI-2qrxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 2qrx GM27569P
(Drosophila
melanogaster) 		4 / 8 HIS A  49
GLN A  46
ARG A  98
GLN A 147
 None
 1.44A 2vxaB-2qrxA:
undetectable
2vxaG-2qrxA:
undetectable
2vxaH-2qrxA:
undetectable		 2vxaB-2qrxA:
14.29
2vxaG-2qrxA:
14.29
2vxaH-2qrxA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 2qrx GM27569P
(Drosophila
melanogaster) 		5 / 9 LEU A 148
ILE A 145
GLY A 144
LEU A 152
SER A 153
 None
 1.08A 3ai9X-2qrxA:
undetectable		 3ai9X-2qrxA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 2qrx GM27569P
(Drosophila
melanogaster) 		3 / 3 GLU A 151
ARG A 154
HIS A  49
 None
 0.74A 4kf9A-2qrxA:
undetectable		 4kf9A-2qrxA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2qrx GM27569P
(Drosophila
melanogaster) 		5 / 12 ASP A 140
VAL A  31
ILE A  34
TYR A  73
LEU A 136
 None
 1.17A 5b8iC-2qrxA:
undetectable		 5b8iC-2qrxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2qrx GM27569P
(Drosophila
melanogaster) 		5 / 11 ASP A 140
VAL A  31
ILE A  34
TYR A  73
LEU A 136
 None
 1.35A 5huaA-2qrxA:
undetectable		 5huaA-2qrxA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 2qrx GM27569P
(Drosophila
melanogaster) 		5 / 10 ASP A 140
VAL A  31
ILE A  34
TYR A  73
LEU A  99
 None
 1.27A 5hw8C-2qrxA:
undetectable
5hw8H-2qrxA:
undetectable		 5hw8C-2qrxA:
18.14
5hw8H-2qrxA:
18.14