SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qs7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_B_LOCB502_2 (TUBULIN BETA CHAIN)	2qs7	UNCHARACTERIZED PROTEIN (Sulfolobus solfataricus)	5 / 12	LYS A 100 LEU A 40 ASN A 39 THR A 140 ALA A 31	None None None EPE A 145 (-4.4A) None	1.15A	4x1iB-2qs7A: undetectable	4x1iB-2qs7A: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	2qs7	UNCHARACTERIZED PROTEIN (Sulfolobus solfataricus)	5 / 12	LYS A 100 LEU A 40 ASN A 39 THR A 140 ALA A 31	None None None EPE A 145 (-4.4A) None	1.08A	4x1kA-2qs7A: undetectable 4x1kB-2qs7A: undetectable	4x1kA-2qs7A: 15.75 4x1kB-2qs7A: 15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_A_SAMA601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	2qs7	UNCHARACTERIZED PROTEIN (Sulfolobus solfataricus)	5 / 12	GLY A 25 HIS A 87 VAL A 90 VAL A 99 VAL A 38	None	1.08A	5dpdA-2qs7A: 2.9	5dpdA-2qs7A: 13.42