SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qs8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.87A 1am6A-2qs8A:
undetectable		 1am6A-2qs8A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 HIS A 255
HIS A 237
HIS A 235
LEU A 202
 MET  A 600 ( 4.3A)
MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 (-3.7A)
 0.97A 1am6A-2qs8A:
undetectable		 1am6A-2qs8A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.83A 1azmA-2qs8A:
undetectable		 1azmA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 255
HIS A 237
HIS A 235
LEU A 202
 MET  A 600 ( 4.3A)
MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 (-3.7A)
 0.96A 1azmA-2qs8A:
undetectable		 1azmA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.80A 1bzmA-2qs8A:
undetectable		 1bzmA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 255
HIS A 237
HIS A 235
LEU A 202
 MET  A 600 ( 4.3A)
MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 (-3.7A)
 0.97A 1bzmA-2qs8A:
undetectable		 1bzmA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 6 HIS A  69
HIS A  71
HIS A 235
HIS A 255
ASP A 328
 MG  A 500 (-3.6A)
MG  A 500 (-3.4A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MG  A 500 ( 2.8A)
 0.90A 1fweC-2qs8A:
19.5		 1fweC-2qs8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 6 HIS A  69
HIS A 150
HIS A 235
HIS A 255
ASP A 328
 MG  A 500 (-3.6A)
MET  A 600 (-4.1A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MG  A 500 ( 2.8A)
 1.24A 1fweC-2qs8A:
19.5		 1fweC-2qs8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 8 PRO A 135
THR A 102
GLY A 106
PHE A  72
THR A 109
 None
 1.30A 1h4oB-2qs8A:
undetectable		 1h4oB-2qs8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 9 PRO A 135
THR A 102
GLY A 106
PHE A  72
THR A 109
 None
 1.33A 1h4oC-2qs8A:
undetectable
1h4oD-2qs8A:
undetectable		 1h4oC-2qs8A:
22.78
1h4oD-2qs8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 9 PRO A 135
THR A 102
GLY A 106
PHE A  72
THR A 109
 None
 1.33A 1h4oH-2qs8A:
0.0		 1h4oH-2qs8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 PHE A 341
LEU A  65
LEU A  62
 None
 0.67A 1mx1E-2qs8A:
undetectable		 1mx1E-2qs8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 LEU A  65
MET A 360
LYS A  20
GLY A  19
 None
 0.98A 1os6A-2qs8A:
undetectable		 1os6A-2qs8A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.91A 2gehA-2qs8A:
undetectable		 2gehA-2qs8A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 SER A 105
VAL A 101
THR A 327
ASP A  67
 None
 0.96A 2hdnF-2qs8A:
2.5
2hdnG-2qs8A:
undetectable
2hdnH-2qs8A:
2.5		 2hdnF-2qs8A:
23.65
2hdnG-2qs8A:
9.97
2hdnH-2qs8A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 6 THR A 327
ASP A  67
SER A 105
VAL A 101
 None
 0.91A 2hdnI-2qs8A:
undetectable
2hdnJ-2qs8A:
2.5
2hdnL-2qs8A:
2.5		 2hdnI-2qs8A:
9.97
2hdnJ-2qs8A:
23.65
2hdnL-2qs8A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.85A 2it4A-2qs8A:
undetectable		 2it4A-2qs8A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 LEU A  10
THR A   9
GLY A  34
ILE A 375
 None
 0.76A 3jusA-2qs8A:
undetectable		 3jusA-2qs8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 LEU A  10
THR A   9
GLY A  34
ILE A 375
 None
 0.76A 3jusA-2qs8A:
undetectable		 3jusA-2qs8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 LEU A  10
THR A   9
GLY A  34
ILE A 375
 None
 0.79A 3jusB-2qs8A:
undetectable		 3jusB-2qs8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 8 LEU A  10
THR A   9
GLY A 407
ALA A 381
ILE A 375
 None
 1.34A 3jusB-2qs8A:
undetectable		 3jusB-2qs8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 9 LEU A  10
THR A   9
GLY A 407
ALA A 381
ILE A 375
 None
 1.34A 3jusB-2qs8A:
undetectable		 3jusB-2qs8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 12 ALA A 280
HIS A 235
HIS A 150
HIS A  69
LEU A 202
 MET  A 600 (-3.4A)
MET  A 600 (-4.4A)
MET  A 600 (-4.1A)
MG  A 500 (-3.6A)
MET  A 600 (-3.7A)
 1.25A 3njzA-2qs8A:
0.0		 3njzA-2qs8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 12 GLY A 148
THR A 147
LYS A 206
VAL A 298
GLY A 156
 None
 0.90A 3sglA-2qs8A:
undetectable		 3sglA-2qs8A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 TYR A 410
MET A  66
LEU A 372
 None
 0.95A 3vw1D-2qs8A:
undetectable		 3vw1D-2qs8A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 GLN A 332
HIS A  69
HIS A  71
LEU A 202
 None
MG  A 500 (-3.6A)
MG  A 500 (-3.4A)
MET  A 600 (-3.7A)
 0.97A 3w6hA-2qs8A:
undetectable		 3w6hA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.84A 3w6hA-2qs8A:
undetectable		 3w6hA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 255
HIS A 237
HIS A 235
LEU A 202
 MET  A 600 ( 4.3A)
MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 (-3.7A)
 1.04A 3w6hA-2qs8A:
undetectable		 3w6hA-2qs8A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 9 ILE A 246
GLY A 249
VAL A 321
THR A 272
GLY A 271
 None
 1.41A 4acaB-2qs8A:
undetectable
4acaC-2qs8A:
2.2		 4acaB-2qs8A:
23.92
4acaC-2qs8A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 ARG A 111
ARG A 367
TRP A 231
 None
 1.46A 4cpzC-2qs8A:
undetectable		 4cpzC-2qs8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 ARG A 111
ARG A 367
TRP A 231
 None
 1.39A 4cpzE-2qs8A:
undetectable		 4cpzE-2qs8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 ARG A 111
ARG A 367
TRP A 231
 None
 1.45A 4cpzF-2qs8A:
undetectable		 4cpzF-2qs8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 ARG A 111
ARG A 367
TRP A 231
 None
 1.40A 4cpzG-2qs8A:
undetectable		 4cpzG-2qs8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 ARG A 111
ARG A 367
TRP A 231
 None
 1.47A 4cpzH-2qs8A:
undetectable		 4cpzH-2qs8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 TYR A 274
THR A 312
GLU A 340
 None
 0.65A 4df3A-2qs8A:
undetectable		 4df3A-2qs8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 TYR A 274
THR A 312
GLU A 340
 None
 0.66A 4df3B-2qs8A:
undetectable		 4df3B-2qs8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 5 HIS A  69
HIS A 150
HIS A 235
HIS A 255
ASP A 328
 MG  A 500 (-3.6A)
MET  A 600 (-4.1A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MG  A 500 ( 2.8A)
 1.28A 4h9mA-2qs8A:
21.0		 4h9mA-2qs8A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 LEU A  65
MET A 360
LYS A  20
GLY A  19
 None
 1.05A 4hbfA-2qs8A:
undetectable		 4hbfA-2qs8A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 LEU A  65
MET A 360
LYS A  20
GLY A  19
 None
 1.03A 4hc3A-2qs8A:
undetectable		 4hc3A-2qs8A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 12 LEU A  16
LEU A  56
ALA A 385
LEU A 383
ILE A  32
 None
 1.07A 4o2bB-2qs8A:
2.8		 4o2bB-2qs8A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 12 LEU A  62
LEU A  65
GLY A  64
VAL A 402
ILE A  37
 None
 0.98A 4ok1A-2qs8A:
undetectable		 4ok1A-2qs8A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 12 LEU A  62
LEU A  65
GLY A  64
VAL A 402
ILE A  37
 None
 1.02A 4oktA-2qs8A:
undetectable		 4oktA-2qs8A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 MET A  68
MET A 230
TYR A 273
 None
 1.42A 4p6xI-2qs8A:
undetectable		 4p6xI-2qs8A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 7 ARG A 136
THR A 108
GLY A  64
THR A 109
 None
 0.92A 4qwpB-2qs8A:
undetectable		 4qwpB-2qs8A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		5 / 6 HIS A  69
HIS A  71
HIS A 235
HIS A 255
ASP A 328
 MG  A 500 (-3.6A)
MG  A 500 (-3.4A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MG  A 500 ( 2.8A)
 0.75A 4ubpC-2qs8A:
19.0		 4ubpC-2qs8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		3 / 3 LEU A  62
VAL A 402
ASP A 401
 None
 0.58A 4y8wC-2qs8A:
undetectable		 4y8wC-2qs8A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2qs8 XAA-PRO DIPEPTIDASE
(Alteromonas
macleodii) 		4 / 8 HIS A 237
HIS A 235
HIS A 255
LEU A 202
 MET  A 600 (-3.9A)
MET  A 600 (-4.4A)
MET  A 600 ( 4.3A)
MET  A 600 (-3.7A)
 0.88A 5tt3H-2qs8A:
undetectable		 5tt3H-2qs8A:
20.74