SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 8 GLY A  19
GLY A  15
LEU A  24
GLY A  48
 None
 0.65A 1d0vA-2qsdA:
undetectable		 1d0vA-2qsdA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 9 VAL A  59
VAL A 106
LEU A 167
ILE A  69
LEU A  10
 None
 1.15A 1eqgA-2qsdA:
undetectable		 1eqgA-2qsdA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 8 GLY A  19
GLY A  15
LEU A  24
GLY A  48
 None
 0.64A 1jhaA-2qsdA:
undetectable		 1jhaA-2qsdA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 8 GLY A  19
GLY A  15
LEU A  24
GLY A  48
 None
 0.68A 1jhqA-2qsdA:
undetectable		 1jhqA-2qsdA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 8 GLY A  19
GLY A  15
LEU A  24
GLY A  48
 None
 0.61A 1jhvA-2qsdA:
undetectable		 1jhvA-2qsdA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 9 GLY A  66
GLN A 165
HIS A  63
ASP A 161
VAL A 108
 None
 1.28A 3fi0D-2qsdA:
undetectable		 3fi0D-2qsdA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 9 GLY A  66
GLN A 165
HIS A  63
ASP A 161
VAL A 108
 None
 1.26A 3fi0J-2qsdA:
undetectable		 3fi0J-2qsdA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 11 ASP A  26
LEU A  55
SER A  57
PHE A  58
ASP A 103
 None
 1.47A 3ko0C-2qsdA:
undetectable
3ko0D-2qsdA:
undetectable
3ko0E-2qsdA:
undetectable
3ko0F-2qsdA:
undetectable		 3ko0C-2qsdA:
22.10
3ko0D-2qsdA:
22.10
3ko0E-2qsdA:
22.10
3ko0F-2qsdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 12 ASP A  26
LEU A  55
SER A  57
PHE A  58
ASP A 103
 None
 1.42A 3ko0G-2qsdA:
undetectable
3ko0H-2qsdA:
undetectable
3ko0I-2qsdA:
undetectable
3ko0J-2qsdA:
undetectable		 3ko0G-2qsdA:
22.10
3ko0H-2qsdA:
22.10
3ko0I-2qsdA:
22.10
3ko0J-2qsdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 11 LEU A  55
SER A  57
PHE A  58
ASP A  26
ASP A 103
 None
 1.41A 3ko0O-2qsdA:
undetectable
3ko0P-2qsdA:
undetectable
3ko0Q-2qsdA:
undetectable
3ko0R-2qsdA:
undetectable		 3ko0O-2qsdA:
22.10
3ko0P-2qsdA:
22.10
3ko0Q-2qsdA:
22.10
3ko0R-2qsdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		5 / 11 ASP A 103
ASP A  26
LEU A  55
SER A  57
PHE A  58
 None
 1.45A 3ko0Q-2qsdA:
undetectable
3ko0R-2qsdA:
undetectable
3ko0S-2qsdA:
undetectable
3ko0T-2qsdA:
undetectable		 3ko0Q-2qsdA:
22.10
3ko0R-2qsdA:
22.10
3ko0S-2qsdA:
22.10
3ko0T-2qsdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 5 ASN A   6
LEU A  71
SER A  73
LEU A 150
 None
 1.23A 4n09C-2qsdA:
undetectable		 4n09C-2qsdA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 4 ASN A   6
LEU A  71
SER A  73
LEU A 150
 None
 1.29A 5kb5A-2qsdA:
undetectable		 5kb5A-2qsdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 6 HIS A  54
ASP A  56
HIS A  25
TRP A  46
 None
 1.33A 5m45A-2qsdA:
0.2		 5m45A-2qsdA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 6 HIS A  54
ASP A  56
HIS A  25
TRP A  46
 None
 1.32A 5m45D-2qsdA:
0.0		 5m45D-2qsdA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 6 HIS A  54
ASP A  56
HIS A  25
TRP A  46
 None
 1.32A 5m45G-2qsdA:
0.0		 5m45G-2qsdA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2qsd UNCHARACTERIZED
CONSERVED PROTEIN
(Idiomarina
loihiensis) 		4 / 6 HIS A  54
ASP A  56
HIS A  25
TRP A  46
 None
 1.32A 5m45J-2qsdA:
0.0		 5m45J-2qsdA:
13.18