SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		3 / 3 LEU A 126
PRO A 127
ARG A  92
 None
 0.55A 2qd5A-2qsjA:
5.5		 2qd5A-2qsjA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		4 / 7 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.79A 2vcvA-2qsjA:
undetectable		 2vcvA-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		4 / 6 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.90A 2vcvB-2qsjA:
undetectable		 2vcvB-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		4 / 7 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.70A 2vcvG-2qsjA:
undetectable		 2vcvG-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		4 / 6 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.98A 2vcvK-2qsjA:
undetectable		 2vcvK-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		4 / 7 PHE A 125
ALA A 107
LEU A 112
ALA A 115
 None
 0.78A 2vcvL-2qsjA:
undetectable		 2vcvL-2qsjA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 LEU A 131
GLY A 101
ILE A  82
ASP A  55
VAL A  56
 None
 1.22A 2zznA-2qsjA:
undetectable		 2zznA-2qsjA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 ALA A  41
LEU A  43
ASN A  47
ALA A  33
ILE A  52
 None
 0.88A 3ut5D-2qsjA:
2.7		 3ut5D-2qsjA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		3 / 3 ASP A 100
LEU A  53
VAL A  36
 None
 0.63A 4jecB-2qsjA:
undetectable		 4jecB-2qsjA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 ALA A  41
LEU A  43
ASN A  47
ALA A  33
ILE A  52
 None
 0.97A 4o2bD-2qsjA:
undetectable		 4o2bD-2qsjA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.43A 4r88A-2qsjA:
undetectable		 4r88A-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.44A 4r88B-2qsjA:
2.3		 4r88B-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.42A 4r88C-2qsjA:
undetectable		 4r88C-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.46A 4r88D-2qsjA:
undetectable		 4r88D-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.42A 4r88E-2qsjA:
undetectable		 4r88E-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 HIS A 114
LEU A  20
GLN A 110
LEU A  21
SER A 117
 None
 1.41A 4r88F-2qsjA:
undetectable		 4r88F-2qsjA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 LEU A  43
ASN A  47
VAL A   7
ALA A  33
ILE A  52
 None
 0.84A 4x1yD-2qsjA:
4.8		 4x1yD-2qsjA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 ALA A  41
LEU A  43
ASN A  47
ALA A  33
ILE A  52
 None
 1.02A 4x20B-2qsjA:
4.4		 4x20B-2qsjA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2qsj DNA-BINDING RESPONSE
REGULATOR, LUXR
FAMILY
(Ruegeria
pomeroyi) 		5 / 12 ALA A  41
LEU A  43
ASN A  47
VAL A   7
ALA A  33
 None
 0.90A 4x20B-2qsjA:
4.4		 4x20B-2qsjA:
17.30