SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2qsr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		4 / 7 LEU A1151
LEU A1071
GLY A1074
TYR A1049
 None
 0.89A 1gtiB-2qsrA:
undetectable		 1gtiB-2qsrA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		5 / 12 ILE A1160
PHE A1099
LEU A1080
VAL A1083
GLU A1159
 None
 1.07A 2bxfA-2qsrA:
undetectable		 2bxfA-2qsrA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		5 / 12 ILE A1160
PHE A1099
LEU A1080
VAL A1083
GLU A1159
 None
 1.09A 2bxfB-2qsrA:
undetectable		 2bxfB-2qsrA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		4 / 6 ILE A1073
ILE A1027
TYR A1026
LEU A1147
 None
 0.74A 3adsA-2qsrA:
undetectable		 3adsA-2qsrA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		4 / 7 ILE A1043
GLY A1074
ASP A1081
PHE A1084
 None
 0.95A 5hieA-2qsrA:
undetectable		 5hieA-2qsrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 2qsr TRANSCRIPTION-REPAIR
COUPLING FACTOR
(Streptococcus
pneumoniae) 		4 / 4 PHE A1136
ASP A1137
LEU A1116
LYS A1122
 None
 1.40A 6awvA-2qsrA:
undetectable		 6awvA-2qsrA:
20.69